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  1. Hepcidin is a peptide hormone produced by the liver and appears to be the master regulator of iron homeostasis. This peptide is upregulated in inflammatory conditions, including uremia. Hepcidin functions to r...

    Authors: Ihab Abdelrahman Ibrahim, Usama M. Mohamad, Hatem A. Darweesh and Amal M. Rashad
    Citation: The Egyptian Journal of Internal Medicine 2014 26:26010006
  2. Although acute myocardial infarction commonly results from coronary atherothrombosis, there are several other etiologies that should be taken initially into account, especially in young adults without signific...

    Authors: Jihen Ayari, Mohamed S. Mourali, Abdjalil Farhati and Rachid Mechmeche
    Citation: The Egyptian Journal of Internal Medicine 2014 26:2602088
  3. Atypical neurological presentations of hypothyroidism include myelopathy which has been seldom reported as presenting feature in patients. This case was one of those atypical presentations of hypothyroidism in...

    Authors: Nimisha Jain, Ramesh Aggarwal, Sachin Kumar Jain, Nitin Garg, Aadhaar Dhooria and Kajal Prasad
    Citation: The Egyptian Journal of Internal Medicine 2014 26:2602086
  4. Skin prick test (SPT) is a gold standard test for diagnosis of allergic [immunoglobulin E (IgE)] diseases. There is a subset of patients who have positive nasal provocation to allergens, despite having a negat...

    Authors: Z. A. Ashour, Hosam Rabee, H. A. El-Melegi, Mohamed Yousef Attia and Hesham Sanad
    Citation: The Egyptian Journal of Internal Medicine 2014 26:2602080
  5. Omentin-1 is a novel adipokine that has a pivotal role in modulating insulin sensitivity, immunity. and inflammation. Adipokines contribute directly to the atherosclerotic process. The current study was conduc...

    Authors: Hend M. Tawfeek, Hala M. Maghrapy, Fadila M. Elsaid and Hanaa Abou Eliazeed
    Citation: The Egyptian Journal of Internal Medicine 2014 26:2602068
  6. Nicotinamide phosphoribosyltransferase (Visfatin), an enzyme involved in the NAD+ salvage pathway, has been shown to help in the regulation of glucose homeostasis. It is a highly conserved, 52 kDa protein foun...

    Authors: Mohamed F. Almaghraby and Abeer A. Mahmoud
    Citation: The Egyptian Journal of Internal Medicine 2014 26:2602045
  7. Gout is a crystal deposition disease caused by raised levels of uric acid in the blood (hyperuricaemia) with persistence of hyperuricemia at levels higher than a serum saturation of 6.8 mg/dl leads to formatio...

    Authors: Hanan Abdel Rehim
    Citation: The Egyptian Journal of Internal Medicine 2014 26:2602035
  8. The aim of this study was to report a rare case of a leaking thoracic aorta aneurysm in a female patient with massive pulmonary embolism. A 70-year-old woman with hypertension who had suffered a cerebral vascu...

    Authors: Shabib Al-Zuabi, Alexander P. Varkey, Safia F. Abdalmaksoud, Hadeel S. Alothman and Ibrahim Alrashdan
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25010047
  9. The clinical implication of insulin resistance has extended beyond diabetes mellitus to include ischemic heart disease, dyslipidemia, hypertension, and features of metabolic syndrome. Nondiabetic patients with...

    Authors: Wael Refaie and Ahmad Elewa
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25010042
  10. Changes in renal nitric oxide (NO) production have been associated with glomerular hyperfiltration, vascular permeability, albuminuria, glomerulosclerosis, and tubulointerstitial fibrosis. This study aimed at ...

    Authors: Mayssa I. Aly, Mohamed N. Abdalla, Mohamed H.F. El Akad, Samar A.E.M. El-Sheikh and Elham M. Yousief
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25010033
  11. Diabetic nephropathy is one of the debilitating complications of type 2 diabetes and the leading cause for end-stage renal disease requiring renal replacement therapy. Currently identified risk factors do not ...

    Authors: Asmaa I. Ahmed, Noha A. Osman, Mohamed M. NasrAllah and Manal M. Kamal
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25010010
  12. A 37-year-old hypertensive housewife presented with a sudden onset of left-sided hemiplegia, hemianaesthesia, dysarthria and urinary incontinence. The condition was preceded by recurrent attacks of motor neuro...

    Authors: Amal F. Radwan, Afaf Hemaida and Ahmed Naguib
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502104
  13. Atherosclerotic renovascular disease (ARVD) is defined as renal artery stenosis with an occlusion of 60% or more. It is an established cause of resistant hypertension and renal insufficiency. ARVD is evaluated...

    Authors: Hesham N. Abdel Mooty, Engie T. Hefnawy, Heba S.H. Kareem and Khaled El Kaffas
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502098
  14. Obstructive sleep apnea (OSA) syndrome is associated with cardiovascular complications attributed to endothelial dysfunction. There are contradictory reports on whether lactoferrin is protective or injurious t...

    Authors: Abir Zakaria, Mostafa El Shazly and Laila Rashed
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502086
  15. Obesity is established as an important contributor of increased diabetes mellitus, hypertension and cardiovascular disease, all of which can promote chronic kidney disease (CKD). Recently, there is a growing a...

    Authors: Wael F. Nassar, Mustafa A. Mustafa, Uomna Kamel, Mohammad H. Hafez, Abdekbaser Saad, Mohammad Anan, Mahmud Temraz, Yaser Hendi, Amir Elokely and Malaka Fouad
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502075
  16. The purpose of this study was to determine the effect of erythropoietin (EPO) treatment on HbA1c levels in diabetic patients on regular hemodialysis and to assess the reliability of HbA1c as a marker for glyce...

    Authors: Mohamed M. Abdel-Aziz, Inas F. Shaltout, Ula M. Al-Jarhi, Yasmine T. Alshewi and Mahmoud M. Elalfy
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502070
  17. There is an established relationship between liver disease and hepatogenous diabetes mellitus, and a growing evidence for the role of vitamin D deficiency in the pathogenesis of type 1 and type 2 diabetes mell...

    Authors: Abir Zakaria, Nagwa Ramadan, Naglaa El-Sayed and Amr Zahra
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502063
  18. The aim of this review was to summarize recent advances in celiac disease (CD) published between 2006 and 2012.

    Authors: Dina I. Shehab
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2502053
  19. A 43-year-old man presented with bony pains, repeated pathological fractures with overlying skin ulcerations, and forearm and chest wall swellings. Investigations led to the diagnosis of Erdheim–Chester diseas...

    Authors: Mohamed A. Hussein, Ali El-Hindawi and Gaafar Ragab
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503159
  20. Diabetic foot problems are highly prevalent, responsible for almost 50% of all diabetes-related hospital admissions and a 10-year reduction in life expectancy. The main factors involved in the pathology of dia...

    Authors: Mary N. Rizk and Ashraf I. Ameen
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503154
  21. As cardiovascular disease is the leading cause of mortality in type 2 diabetes mellitus, new markers for early detection and risk stratification of diabetic macroangiopathy and microangiopathy are highly desir...

    Authors: Ibtissam Zakaria, Mary N. Rizk, Maha Rakha and Amal Shehaby
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503143
  22. Dyslipidemia has long been implicated in diabetic complications. However, many subgroups have been considered to be responsible. Furthermore, a cause and effect relationship has long been debated. Apolipoprote...

    Authors: Mary N. Rizk, Hala Aly, Pierre Samir, Hala el Mofty and Osama K. Allah
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503137
  23. Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetic nephropathy is the major microvascular complicat...

    Authors: Ebtissam Zakaria, Hoda Al-Rawi, Nashwa S. Ghanem, Naglaa M. Elsayed and Laila A. Rashed
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503133
  24. Although there are considerable data on the changes in left ventricular function in hemodialysis (HD) patients, only a few studies on right ventricular (RV) function can be found in the literature. We investig...

    Authors: Mohamed Momtaz, Hussein Al Fishawy, Ula Mabid Aljarhi, Rabei Z. Al-Ansi, Mohamed A. Megid and Mahmoud Khaled
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503127
  25. This study investigated the utility of measuring plasma long pentraxin 3 (PTX3) levels in the early detection of endothelial dysfunction compared with Von Willebrand factor (vWF) activity and flow-dependent ar...

    Authors: Amr A. El Meligi, Alaa M. Abdel Hamid, Manal A. Aziz, Hemmat E. El Haddadd, Marian F. Ishak and Elham M. Yousief
    Citation: The Egyptian Journal of Internal Medicine 2014 25:2503117
  26. 30 yrs old man is known to have thalassemia intermedia presented with bilateral lower limb weakness and sphincteric troubles with loss of deep sensations, the motor power of the muscles and precipitancy of uri...

    Authors: Aysha I. Z. Badawi, Mona I. Nabih, Noha K. H. M. Khalil, Mohamed A. A. ELnady and Sarra A. Hassan
    Citation: The Egyptian Journal of Internal Medicine 2014 26:26010027
  27. Patients either with or without a prior history of diabetes mellitus may present with hyperglycemia during acute myocardial infarction (AMI); it is uncertain whether hyperglycemia upon admission, irrespective ...

    Authors: Hanan E. Zaghla, Mahmoud A. Elbadry, Alaa M. Ashour and Mohamed M. Abdelfatah
    Citation: The Egyptian Journal of Internal Medicine 2014 26:26010021
  28. Toll-like receptors (TLRs) are essential molecules of the innate immune system that stimulate numerous inflammatory pathways and harmonize systemic defense against a wide array of pathogens. TLRs may also reco...

    Authors: Hanan A. Taha, Rania E. Sheir, Sanaa S. Abdel Shafy and Lamya M. Mohamed
    Citation: The Egyptian Journal of Internal Medicine 2014 26:26010015
  29. Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective...

    Authors: Samar H. Aboulsoud
    Citation: The Egyptian Journal of Internal Medicine 2014 26:26010001
  30. Cardiovascular disease has increased as a complication of chronic kidney disease even in the absence of diabetes or hypertension. Angiopoietin-1 and 2 are 55 kDa antagonistic nonredundant gatekeepers of endoth...

    Authors: Fatma A. Attia, Nagwa A. Mohammed and Al-Shymaa A. Ibrahim
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040225
  31. Fetuin-A is a circulating inhibitor of calcium deposition in the vasculature and may be involved in the pathogenesis of cardiovascular disease. Low plasma fetuin-A level is independently associated with increa...

    Authors: Amani K. Mohamed, Amany M. Abdallah, Maha A. Hassan, Nagwa A. Mohammed and Solaf A. Kamel
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040218
  32. Chronic hepatitis C virus (HCV) infection affects around 170 million individuals worldwide. Egypt has one of the highest prevalence of patients with HCV worldwide. A higher prevalence of insulin resistance (IR...

    Authors: Ebtissam Zakaria, Tarek Fayad, Mary N. Rizk, Nashwa S. Ghanem and Maisa Kamal
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040213
  33. Obesity is a chronic condition that is associated with disturbances in the metabolism of zinc. Therefore, the aim of this study was to investigate the relationship between serum zinc level and different clinic...

    Authors: Doaa S. E. Zaky, Eman A. Sultan, Mahmoud F. Salim and Rana S. Dawod
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040209
  34. Endothelial dysfunction, atherosclerosis, and cardiovascular disease are strongly linked to chronic kidney disease. It has been hypothesized that visfatin may play an important role in uremia-related atheroscl...

    Authors: Abdel Wahab M. Lotfy, Nagwa A. Mohammed, Hanan M. El-Tokhy and Fatma A. Attia
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040202
  35. In patients with liver cirrhosis and portal hypertension (PHT), portal hypertensive colopathy (PHC) is thought to be an important cause of lower gastrointestinal bleeding. This study aimed at evaluating the pr...

    Authors: Zakaria A. Salama, Ahmad N. Hassan and Samar K. Darweesh
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040196
  36. It has been suggested that admission hyperglycemia is a marker of extensive brain damage. Despite these observations, studies that have examined the relationship between glucose levels and the outcome after st...

    Authors: Kamel Abdelaziz Mohamed and Ahmad Saad
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040185
  37. Oxidative modification of low-density lipoproteins (LDLs) induces formation of immunogenic epitopes in the LDL molecule, which leads to the formation of antibodies against oxidized low-density lipoprotein (OxL...

    Authors: Mohamed S. Mokhtar, Hanan E. Hassan Zaghla, Wael Samy and Abdou Mahmoud
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040177
  38. Thyroid hormones influence heart rate, serum lipids, metabolic rate, body weight, and multiple aspects of lipid, carbohydrate, protein, and mineral metabolism. Although increased thyroid hormone levels can imp...

    Authors: Randa F. Salam
    Citation: The Egyptian Journal of Internal Medicine 2014 25:25040171