The severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was initially identified in Wuhan, Hubei, China, in late December of 2019 . The SARS-COV-2 is responsible for a multi-systemic infectious disease named COVID-19, which manifest with wide range of respiratory, gastrointestinal, neurological, and etc. signs and symptoms [2,3,4,5]. The ongoing COVID-19 pandemic has affected many lives worldwide. Until 1 August 2020, more than 17,100,000 individuals have been infected with the SARS-COV-2, resulting in more than 668,000 death cases [3, 6]. SARS-COV-2 can easily spread through respiratory droplets and close individual contacts . Infected individuals are assumed to transmit the COVID-19 during the incubation period, which is estimated to be about 2 to 14 days. While some of COVID-19 patients are known to be asymptomatic, symptomatic patients mostly present with cough and fever. Other symptoms include dyspnea, myalgia, confusion, headache, diarrhea, nausea, and vomiting [1, 2, 8, 9].
Social distancing and early isolation of infected individuals play crucial roles in the controlling the COVID-19 outbreak. Furthermore, the definite diagnosis of COVID-19 is made based on the real-time polymerase chain reaction (RT-PCR). However, physicians’ clinical suspicion is still the leading part of diagnosis. Since the clinical sign and symptoms of COVID-19 are very similar to that of various respiratory diseases, the diagnosis of COVID-19 can be challenging. In this regard, the chest computed tomography (CT) scan such as ground glass opacity and hematological findings (lymphocytopenia) can be helpful . Nevertheless, due to the context of COVID-19 pandemic, and its importance, many other respiratory infectious diseases such as tuberculosis (TB) may miss . In this regard, TB is the cause of more than 1.2 million deaths per year, globally. COVID-19 and TB are diseases that affect the lungs and respiratory airways primarily. These two diseases have resembling symptoms, including dry cough, fever, and dyspnea . Herein, a case of COVID-19 and tuberculosis co-infection is presented.