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BCR/ABL positive thrombocythemia: a diagnostic dilemma

The Egyptian Journal of Internal Medicine volume 29, pages 83–85 (2017)Cite this article

Abstract

Both chronic myeloid leukemia and essential thrombocythemia are part of the spectrum of myeloproliferative neoplasm. Therefore, considerable overlap may occur in the clinical manifestations, and hematological and molecular findings in some patients. We report here a case of a 45-year-old men who presented with thrombocytosis. Bone marrow aspiration yielded small megakaryocytes with hypolobulated nuclei and positive BCR-ABL rearrangement. A diagnosis of BCR-ABL+ essential thrombocythemia was made and imatinib was advised.

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Authors and Affiliations

  1. Departments of Medicine, Aligarh Muslim University, 4/1074, Sir Syed Nagar, Near Nadeem Tarin Hall, Aligarh, Uttar Pradesh, 202 002, India

    Lubna Zafar MBBS, MD (Medicine), Anjum Parvez & Srikant Behera

  2. Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

    Feroz Alam

Authors
  1. Lubna Zafar MBBS, MD (Medicine)
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  2. Feroz Alam
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  3. Anjum Parvez
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  4. Srikant Behera
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Correspondence to Lubna Zafar MBBS, MD (Medicine).

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Zafar, L., Alam, F., Parvez, A. et al. BCR/ABL positive thrombocythemia: a diagnostic dilemma. Egypt J Intern Med 29, 83–85 (2017). https://doi.org/10.4103/ejim.ejim_21_16

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  • DOI: https://doi.org/10.4103/ejim.ejim_21_16

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