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Bicuspid aortic valve associated with aortic thrombotic occlusion


The bicuspid aortic valve is associated with disorders of the aortic wall, including coarctation of the aorta and aortic dissection. The histologic abnormality underlying aortic complications in bicuspid aortic valve is cystic medial necrosis. The elastic properties of the aorta are abnormal in bicuspid aortic valve. Here, we present a case of aortic thrombotic occlusion in a patient with a bicuspid aortic valve.


  1. Mancuso D, Basso C, Cardaioli P, Thiene G. Clefted bicuspid aortic valve. Cardiovasc Pathol 2002; 11:217–220.

    Article  Google Scholar 

  2. Leriche R, Morel A. The syndrome of thrombotic obliteration of the aortic bifurcation. Ann Surg 1943; 127:193–206.

    Article  Google Scholar 

  3. Eisenberg LM, Markwald RR. Molecular regulation of atrioventricular valvuloseptal morphogenesis. Circ Res 1995; 77:1–6.

    CAS  Article  Google Scholar 

  4. Bonderman D, Gharehbaghi-Schnell E, Wollenek G, Maurer G, Baumgartner H, Lang IM. Mechanisms underlying aortic dilatation in congenital aortic valve malformation. Circulation 1999; 99: 2138–2143.

    CAS  Article  Google Scholar 

  5. Fedak PW, de Sa MP, Verma S, Nili N, Kazemian P, Butany J, et al. Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation. J Thorac Cardiovasc Surg 2003; 126:797–806.

    Article  Google Scholar 

  6. Surowiec SM, Isiklar H, Sreeram S, Weiss VJ, Lumsden AB. Acute occlusion of the abdominal aorta. Am J Surg 1998; 176:193–197.

    CAS  Article  Google Scholar 

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Correspondence to Altuğ Ösken MD.

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Zehir, R., Ösken, A., Öz, T.K. et al. Bicuspid aortic valve associated with aortic thrombotic occlusion. Egypt J Intern Med 28, 128–130 (2016).

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  • aortic occlusion
  • bicuspid aortic valve
  • Leriche syndrome