- Original article
- Open Access
Renal transplantation experience in Cairo University hospitals
The Egyptian Journal of Internal Medicine volume 28, pages 116–122 (2016)
Worldwide, the population treated with renal replacement therapy is increasing, representing ~1.3 million patients who undergo dialysis and 400 000 patients who are alive with a kidney transplant. Transplantation is more predictable than it was 20–30 years ago and innovation over the last 20 years has been rapid, delivering substantial short-term and medium-term improvements. Many reports have been published about the epidemiology of renal transplantation in different countries. The aim of this study was to identify the epidemiology of renal transplantation in Cairo University hospitals.
Patients and methods
This is a retrospective study that was conducted at the King Fahd Unit, Faculty of Medicine, Cairo University, on 282 patients. All patients were followed up for a period of at least 1 year. Demographic data, history taking, clinical examination, immunosuppressive medications protocol, and laboratory investigations were recorded for every patient.
Of the 282 patients included in the study, 68.1% of recipients were male and 31.9% were female, whereas 52.5% of donors were male and 47.5% were female. An overall 98.6% of our patients received living kidney transplants, whereas 1.4% received cadaveric kidney transplants. The most common cause of end-stage renal disease was unknown etiology. The mean BMI increased significantly after transplantation to reach 22.6±4.0 (P=0.0001). Hypertension was the most common disease among the patients; 82.2% of our patients were already hypertensive before transplantation.
The majority of our recipients were male patients in their second and third decades of life, Moreover, the majority of donors were also male individuals in their second and third decades of life. Most of the transplants carried out by us are living-donor procedures.
Garcia-Garcia G, Harden P, Chapman J. The global role of kidney transplantation. Indian J Nephrol 2012; 22:77–82.
Bakr MA. Renal transplantation in Egypt. Organs Tissues 2000; 1:39–44.
Barsoum R, Bakr MA. The Egyptian renal transplant experience. Clin Transpl 2000; 359–360.
Matas AJ, Smith JM, Skeans MA, Thompson B, Gustafson SK, Schnitzler MA, et al. OPTN/SRTR 2012 annual data report: kidney. Am J Transplant 2014; 14(Suppl 1):11–44.
Ellison MD, McBride MA, Taranto SE, Delmonico FL, Kauffman H. Living kidney donors in need of kidney transplants: a report from the Organ Procurement and Transplantation Network. Transplantation 2002; 74:1349–1353.
Amaral S, Sayed BA, Kutner N, Patzer RE. Preemptive kidney transplantation is associated with survival benefits among pediatric patients with end-stage renal disease. Kidney Int 2016; 90:1100–1108.
Bakr M, Refaie A, Hassan N, et al. Rescue therapy with tacrolimus and MMF after live-donor kidney transplantation. Afr J Nephrol 2005.
Baid-Agrawal S, Pascual M, Moradpour D, Muche M. Hepatitis C virus infection and kidney transplantation in 2014: what’s new? Am J Transplant 2014; 14:2206–2220.
Aull MJ, Afaneh C, Kapur S. Complications of kidney transplantation: effects of over-immunosuppression 2012. doi.org/10.5772/53672.
Pascual M, Theruvath T, Kawai T, et al. Strategies to improve longterm outcomes after renal transplantation. N Engl J Med 2002; 346: 580–590.
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work noncommercially, as long as the author is credited and the new creations are licensed under the identical terms
About this article
Cite this article
Saadi, M.G., El-Khashab, S.O. & Mahmoud, R.M.A. Renal transplantation experience in Cairo University hospitals. Egypt J Intern Med 28, 116–122 (2016). https://doi.org/10.4103/1110-7782.200967
- Cairo University