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The Egyptian Journal of Internal Medicine
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Undifferentiated spondyloarthritis is more frequently seen in women than in men

The Egyptian Journal of Internal Medicine volume 27, pages 53–57 (2015)Cite this article

Abstract

Introduction

Spondyloarthritis (SpA) are a group of inflammatory rheumatic diseases that share some common clinical and genetic features such as inflammatory back pain, peripheral arthritis, enthesitis, anterior uveitis, sacroiliitis, and HLA-B27 positivity. The aim of the present study was to describe the clinical, radiologic, and genetic features of patients with undifferentiated spondyloarthritis (uSpA) and ankylosing spondylitis (AS).

Patients and methods

This study included 225 SpA patients (134 uSpA and 91 AS) attending our Rheumatology Outpatient Clinic consecutively. Patients underwent peripheral and axial joint and enthesitis assessment, erythrocyte sedimentation rate or C-reactive protein determination, HLA-B27 tissue typing, radiographic evaluation, and sacroiliac MRI.

Results

In total, 26 of 91 AS patients and 115 of 134 uSpA patients were women (28.6 vs. 85.8%) and 65 of AS and 19 of uSpA were men (71.4 vs. 14.2%). The time for diagnosis was 15.82 ± 20.7 months for AS patients and 5.91 ± 3.63 months for uSpA patients. Diagnostic delay was 102.46 ± 88.99 (median 83, range 8–377) months for AS and 74.23 ± 60.7 (median 55.5, range 0–238) months for uSpA patients. HLA-B27 positivity was present in 51.6% of AS and 14.9% of uSpA patients. The mean BASDAI level of patients with AS was 6.4 ± 1.1 and that of uSpA patients was 4.8 ± 2.1.

Conclusion

SpA are frequent diseases and physicians other than rheumatologists should also be aware of them. uSpA is more frequent in women than men. Early diagnosis of SpA is important because early treatment with new biological therapies may lead to much better results than applying them in the advanced stages.

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Authors and Affiliations

  1. Department of Rheumatology, Yıldırım Beyazıt University Atatürk Education and Research Hospital, Ankara, Turkey

    Sukran Erten & Orhan Küçükşahin MD

  2. Department of Radiology, Yıldırım Beyazıt University Atatürk Education and Research Hospital, Ankara, Turkey

    Ali Sahin

  3. Department of Molecular Genetics, Yıldırım Beyazıt University Atatürk Education and Research Hospital, Ankara, Turkey

    Nurdan Cay

  4. Department of Rheumatology, Cumhuriyet University Education and Research Hospital, Sivas, Turkey

    Gulay G. Ceylan

Authors
  1. Sukran Erten
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  2. Orhan Küçükşahin MD
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  3. Ali Sahin
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  4. Nurdan Cay
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  5. Gulay G. Ceylan
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Corresponding author

Correspondence to Orhan Küçükşahin MD.

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Erten, S., Küçükşahin, O., Sahin, A. et al. Undifferentiated spondyloarthritis is more frequently seen in women than in men. Egypt J Intern Med 27, 53–57 (2015). https://doi.org/10.4103/1110-7782.158000

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  • DOI: https://doi.org/10.4103/1110-7782.158000

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