Skip to main content
The Egyptian Journal of Internal Medicine
Download PDF

Aluminium phosphide induced acute kidney injury

The Egyptian Journal of Internal Medicine volume 27, pages 115–117 (2015)Cite this article

Abstract

Aluminium phosphide is one of the most common agricultural poisons being consumed in north India. Consumption of a fresh tablet is lethal as no antidote is available. Acute intoxication primarily presents with cardiovascular collapse due to myocardial toxicity. We report here a case of acute severe poisoning along with cardiovascular collapse and oliguria. The patient developed acute kidney injury during the illness (a rare entity in aluminium phosphide poisoning), which completely resolved following prompt conservative treatment.

References

  1. Siwach SB, Yadav DR, Arora B, Dalal S, Jagdish. Acute aluminum phosphide poisoning–an epidemiological, clinical and histo-pathological study. J Assoc Physicians India 1988; 36: 594–596.

    CAS  PubMed  Google Scholar 

  2. Singh D, Dewan I, Pandey AN, Tyagi S. Spectrum of unnatural fatalities in the Chandigarh zone of north-west India–a 25 year autopsy study from a tertiary care hospital. J Clin Forensic Med 2003; 10: 145–152.

    Article  Google Scholar 

  3. Hajouji Idrissi M, Oualili L, Abidi K, Abouqal R, Kerkeb O, Zeggwagh AA. Severity factors of aluminium phosphide poisoning (Phostoxin). Ann Fr Anesth Reanim 2006; 25: 382–385.

    Article  CAS  Google Scholar 

  4. Bajwa SJS, Kaur SKB, Kaur J, Singh K, Panda A. Management of celphos poisoning with a novel intervention: a ray of hope in the darkest of clouds. Anaesth Essays Res 2010; 4: 20–24.

    Article  Google Scholar 

  5. Wahab A, Zaheer MS, Wahab S, Khan RA. Acute aluminium phosphide poisoning: an update. Hong Kong J Emerg Med 2008; 3: 152–155.

    Article  Google Scholar 

  6. Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J 2006; 23: e3.

    Article  CAS  Google Scholar 

  7. Nocera A, Levitin HW, Hilton JM. Dangerous bodies: a case of fatal aluminium phosphide poisoning. Med J Aust 2000; 173: 133–135.

    Article  CAS  Google Scholar 

  8. Chefurka W, Kashi KP, Bond EJ. The effect of phosphine on electron transport in mitochondria. Pestic Biochem Physiol 1976; 6: 65–84.

    Article  CAS  Google Scholar 

  9. Graham DL, Laman D, Theodore J, Robin ED. Acute cyanide poisoning complicated by lactic acidosis and pulmonary edema. Arch Intern Med 1977; 137: 1051–1055.

    Article  CAS  Google Scholar 

  10. Singh S, Singh D, Wig N, et al. Aluminum phosphide ingestion: a clinico-pathologic study. J Toxicol Clin Toxicol 1996; 34: 703–706.

    Article  CAS  Google Scholar 

  11. Gupta MS, Mehta L, Chugh SN, Malhotra KC. Aluminium phosphide poisoning. Two cases with rare presentation. J Assoc Physicians India 1990; 38: 509–510.

    CAS  PubMed  Google Scholar 

  12. Jain SM, Bharani A, Sepha GC. Electrocardiographic changes in aluminium phosphide poisoning. J Assoc Physc India 1985; 33: 406–409.

    CAS  Google Scholar 

  13. Chugh SN, Kumar P, Aggarwal HK, Sharma A, Mahajan SK, Malhotra KC. Efficacy of magnesium sulphate in aluminium phosphide poisoning – comparison of two different dose schedules. J Assoc Physicians India 1994; 42: 373–375.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, 202002, Aligarh, Uttar Pradesh, India

    Quaiser Saif, Khan Ruhi MD, DNB & Sharma Aparna

Authors
  1. Quaiser Saif
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Khan Ruhi MD, DNB
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sharma Aparna
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Khan Ruhi MD, DNB.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Saif, Q., Ruhi, K. & Aparna, S. Aluminium phosphide induced acute kidney injury. Egypt J Intern Med 27, 115–117 (2015). https://doi.org/10.4103/1110-7782.157999

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/1110-7782.157999

Keywords