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The Egyptian Journal of Internal Medicine
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Oncocytic adrenal tumour presenting as Cushing syndrome: rare presentation of a rare tumour

The Egyptian Journal of Internal Medicine volume 26, pages 184–185 (2014)Cite this article

Abstract

Oncocytic neoplasms are well recognized in organs such as the kidney, thyroid and salivary glands. They are seen rarely in other sites such as the adrenal cortex. To date, around 20 cases of oncocytic adrenocortical neoplasm have been reported; most of them were benign and nonfunctioning. We report the case of hypersecreting adrenocortical oncocytoma in a 52-year-old woman. The patient was tested because of cushingoid features. The patient underwent a laparotomy for right adrenal gland mass. The pathology report confirmed adrenocortical oncocytoma.

References

  1. Hamperi H. Contributions to normal pathological and histological human saliva drusen. Z Microanaf researchers 1931;27:1.

    Google Scholar 

  2. Chang A, Harawi SJ. Oncocytes, oncocytosis, and oncocytic tumors. Pathol Annu 1992; 27:263–304.

    PubMed  Google Scholar 

  3. Rouzbahman M, Serra S, Chetty R. Rectal adenocarcinoma with oncocytic features: possible relationship with preoperative chemoradiotherapy. J Clin Pathol 2006; 59:1039–1043.

    Article  CAS  Google Scholar 

  4. Vancura RW, Thomas JH, Jewell WR, Damjanov I. Bilateral oncocytic malignant melanoma in axillary lymph nodes without evidence of an extranodal primary. Ultrastruct Pathol 2005; 29:399–404.

    Article  Google Scholar 

  5. Radi MJ, Fenoglio-Preiser CM, Chiffelle T. Functioning oncocytic islet-cell carcinoma. Report of a case with electron-microscopic and immunohistochemical confirmation. Am J Surg Pathol 1985; 9:517–524.

    CAS  PubMed  Google Scholar 

  6. Bisceglia M, Ludovico O, Di Mattia A, Ben-Dor D, Sandbank J, Pasquinelli G, et al. Adrenocortical oncocytic tumors: report of 10 cases and review of the literature. Int J Surg Pathol 2004; 12:231–243. Neoplastic cells with pink granular cytoplasm and brown pigmentation.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Medicine, Sri Aurobindo Medical College, Indore, Madhya Pradesh, 453555, India

    Abhishek Singhai

  2. Department of Endrocrinology, Sri Aurobindo Medical College, Indore, Madhya Pradesh, India

    Subodh Banzal

Authors
  1. Abhishek Singhai
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  2. Subodh Banzal
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Correspondence to Abhishek Singhai.

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Singhai, A., Banzal, S. Oncocytic adrenal tumour presenting as Cushing syndrome: rare presentation of a rare tumour. Egypt J Intern Med 26, 184–185 (2014). https://doi.org/10.4103/1110-7782.148180

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  • DOI: https://doi.org/10.4103/1110-7782.148180

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