The Egyptian Journal of Internal Medicine

Table 5 Relation between age and daily Levothyroxine dose and weight-based L-T4 dose in group 3: Overt hypothyroidism

From: Real-world derived weight-based levothyroxine doses to achieve optimal thyrotropin target in different degrees of autoimmune hypothyroidism

Group 3: OH (n = 75)	Age (years)		p
Group 3: OH (n = 75)	< 60 (n = 56)	≥ 60 (n = 19)	p
Daily L-T4 dose
Mean ± SD	120.0 ± 33.73	104.8 ± 21.89	0.108
Median (min.–max.)	114.0 (43.0–250.0)	107.0 (57.0–143.0)	0.108
L-T4 dose (µg/kg/day)
Mean ± SD	1.45 ± 0.31	1.27 ± 0.18	0.030^*
Median (min.–max.)	1.40 (0.61–2.45)	1.28 (0.85–1.54)	0.030^*

SD standard deviation
p p value for comparing between patients < 60 and ≥ 60 years of age
^*Statistically significant at p ≤ 0.05

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