Skip to main content

Table 2 Laboratory investigation results of the studied population

From: Epidemiology, risk factors, outcomes, and role of Serpin A3 as a biomarker for transition of acute kidney injury to chronic kidney disease in critically ill patients

 

Transition of AKI to CKD

p-value

Negative (n = 201)

Positive (n = 51)

CBC

Hemoglobin (g/dl)

9.71 ± 2.9

9.22 ± 2.5

 = 0.364*

WBCs*103/l

14 (1–59)

15 (2.5–48)

 = 0.350**

Platelet*103/l

200 (4–1058)

235 (11–500)

 = 0.145**

KFT

BUN (mmol/l)

26 (6–79)

31 (12–87)

 = 0.024**

S. creatinine (µmol/l)

296 (171–1576)

412 (187–1456)

 = 0.002**

Blood electrolytes

Na (mEq/l)

134.47 ± 8.6

133.29 ± 9.1

 = 0.417*

K (mmol/l)

4 (1–8)

4.5 (1–10)

 = 0.049**

Ca (mg/dl)

8.5 (3–11)

8.2 (3–9.5)

 = 0.123**

PO4 (mg/dl)

3 (1–13)

4 (1–10)

 = 0.002**

Mg (mg/dl)

2 (1.1–5.5)

2 (1–5)

 = 0.598**

LFT

AST (U/l)

53 (6–3569)

59 (14–3689)

 = 0.479**

ALT (U/l)

40 (6–4182)

43 (10–3120)

 = 0.735**

Albumin (g/l)

30 (3–129)

31 (19–45)

 = 0.060**

TB (µmol/l)

10 (1–339)

9 (1–132)

 = 0.532**

DB (µmol/l)

6 (0.1–282)

4 (0.4–107)

 = 0.392**

Coagulation profile

PT(s)

16 (11–43)

15.5 (11–34)

 = 0.811**

PC

56 (19–104)

61.5 (21–77)

 = 0.858**

INR

1.5 (1.1–3.9)

1.3 (1.1–3.3)

 = 0.447**

Serpin level

Serum serpin (ng/ml)

74 (57.5–307)

169.5 (118–171)

 = 0.015**

Urinary serpin (ng/ml)

67 (40.5–147)

150 (114–282)

 = 0.005**

Urine analysis

PUS

12 (1–100)

20 (5–100)

 = 0.001**

RBCs

5 (0–100)

5 (1–100)

 = 0.954**

Other findings

• Cast

5 (2.5%)

2 (4%)

 = 0.824***

• Albumin

57 (28.4%)

15 (29.4%)

 = 0.882$

• 24-h protein

14 (7%)

4 (7.8%)

 = 0.828***

Imaging

Abnormal findings

  • U/S

79 (39.3%)

24 (47.1%)

 = 0.048$

  • Chest CT

107 (53.2%)

29 (56.9%)

 = 0.380$

  • Echo

67 (33.3%)

29 (56.9%)

 = 0.002$

Renal biopsy

  • Yes

5 (2.5%)

1 (2%)

 = 0.649***

  1. *Independent sample t-test was used to compare the differences in mean between groups
  2. **Mann–Whitney U t-test was used to compare the differences in median between groups
  3. ***Fisher’s exact test was used to compare the frequency differences between groups. $Chi-square test was used to compare the frequency differences between groups