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Table 1 Baseline characteristics of the studied cases

From: Epidemiology, risk factors, outcomes, and role of Serpin A3 as a biomarker for transition of acute kidney injury to chronic kidney disease in critically ill patients

 

Transition of AKI to CKD

p-value

Negative (n = 201)

Positive (n = 51)

Age/years

56.26 ± 17.7

63.84 ± 13.9

 = 0.005*

Sex

• Female

84 (41.8%)

13 (25.5%)

 = 0.033**

• Male

117 (58.2%)

38 (74.5%)

 

Comorbidity

• DM

85 (42.3%)

26 (51%)

 = 0.264**

• HTN

75 (37.3%)

25 (49%)

 = 0.127**

• Cardiac

49 (24.4%)

29 (56.9%)

 = 0.001**

• Hepatic

49 (24.4%)

6 (11.8%)

 = 0.051**

• Chest

17 (8.5%)

6 (11.8%)

 = 0.464**

• Hematology

5 (2.5%)

3 (5.9%)

 = 0.217***

• Malignancy

29 (14.4%)

7 (13.7%)

 = 0.898**

• Endocrine

10 (5%)

3 (5.9%)

 = 0.749***

• CVS

20 (10%)

11 (21.6%)

 = 0.024**

• Autoimmune

14 (7%)

1 (2%)

 = 0.317***

LHS/days

9.25 ± 1.5

10.29 ± 1.9

 = 0.331*

Risk factor

• Bleeding

33 (16.4%)

11 (21.6%)

 = 0.387**

• Dehydration

65 (32.3%)

12 (23.5%)

 = 0.223**

• Shock

69 (34.3%)

14 (27.5%)

 = 0.351**

• Infection

157 (78.1%)

44 (86.3%)

 = 0.195**

• Drugs

16 (8%)

8 (15.7%)

 = 0.093**

• Contrast

6 (1.5%)

3 (5.9%)

 = 0.319***

• Obstruction

3 (1.5%)

4 (7.8%)

 = 0.014**

• GN

2 (1%)

1 (2%)

 = 0.494***

• Others

22 (10.9%)

4 (7.8%)

 = 0.515**

  1. *Independent sample t-test was used to compare the differences in mean between groups
  2. **Chi-square test was used to compare the frequency differences between groups
  3. ***Fisher’s exact test was used to compare the frequency differences between groups. Cardiac (acute coronary syndrome, congestive HF, IHD, valvular heart disease). Hepatic (liver cirrhosis, hepatic malignancy). Hematological (anemias, hematologic malignancy). Endocrinal (thyroid dysfunction)