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Table 1 Demographic, clinical and laboratory findings of the studied patients

From: Role of serum micro-RNA 486-5p in Egyptian cirrhotic hepatitis C patients with hepatocellular carcinoma

 

Without HCC (n = 25)

HCC (n = 25)

Test of sig.

p

Gender

 Male

15 (60.0%)

20 (80.0%)

χ2 = 2.381

0.123

 Female

10 (40.0%)

5 (20.0%)

Age (years) (mean ± SD)

60.72 ± 10.60

59.64 ± 7.54

t = 0.415

0.680

Ascites

 Absent

3 (12.0%)

4 (16.0%)

χ2 = 4.378

MCp = 0.367

 Grade 1

7 (28.0%)

8 (32.0%)

 Grade 2

6 (24.0%)

9 (36.0%)

 Grade 3

9 (36%)

4 (16%)

Encephalopathy

 Grade 0

15 (60.0%)

17 (68.0%)

χ2 = 2.329

MCp = 0.581

 Grade 1

5 (20.0%)

5 (20.0%)

 Grade 2

0 (0.0%)

1 (4.0%)

 Grade 3

5 (20.0%)

2 (8.0%)

Hb (mean ± SD) (g/dl)

9.26 ± 2.04

10.53 ± 2.36

t = 2.033*

0.048*

RBCs (mean ± SD) (million/mm3)

3.34 ± 0.65

3.61 ± 0.97

t = 1.163

0.250

WBCs (microliters)

 Min.–Max

1.90–14.06

0.02–44.19

U = 259.5

0.304

 Median (IQR)

5.79 (3.95–9.12)

7.14 (5.54–9.48)

Platelets (thousand/microliters)

 Min.–Max

9–308

20–273

U = 270.0

0.410

 Median (IQR)

96 (65.0–120.0)

110 (60.0–178.0)

SGOT (U/L)

 Min.–Max

16–130

16–430

U = 110.5*

 < 0.001*

 Median (IQR)

45 (35.0–51.0)

97 (58.0–130.0)

SGPT (U/L)

 Min.–Max

12–85

20–449

U = 189.5*

0.017*

 Median (IQR)

34 (29.0–37.0)

47 (31.0–80.0)

Bilirubin (mg/dl)

 Min.–Max

0.50–16.0

0.70–20.0

U = 163.0*

0.004*

 Median (IQR)

1.40 (0.80–2.20)

2.40 (1.80–6.90)

INR (mean ± SD)

1.37 ± 0.21

1.45 ± 0.30

t = 1.101

0.276

Albumin (mean ± SD) (g/dl)

2.50 ± 0.52

2.62 ± 0.71

t = 0.683

0.498

Child score (mean ± SD)

9.28 ± 1.46

9.24 ± 1.79

t = 0.087

0.931

Child grade

 A

1 (4.0%)

2 (8.0%)

χ2 = 0.638

0.824

 B

10 (40.0%)

11 (44.0%)

 C

14 (56.0%)

12 (48.0%)

  1. Hb hemoglobin, sGOT serum glutamic oxaloacetic transaminase, RBCs red blood cells, sGPT serum glutamic pyruvic transaminase, WBCs white blood cells, INR international normalization ratio, SD standard deviation, p p value for comparing the two studied groups
  2. *Statistically significant at p ≤ 0.05