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Table 7 Diagnostic performance characters of the estimated levels of the studied lab variate for UC diagnosis

From: Evaluation of the diagnostic performance of estimated fecal calprotectin and serum intelectin-1 and C-reactive protein solo or in combination for differentiation between patients with query ulcerative colitis and irritable bowel syndrome

Variate

MES

Microscopic diagnosis

FCP

CRP

ITLN1

FCP

CRP

ITLN1

Cutoff point

 > 150 µg/ml

 > 5 mg/L

 ≤ 30 ng/ml

 > 150 µg/ml

 > 5 mg/L

 ≤ 18 ng/ml

Sensitivity

Rate (%)

27.9

78.7

81.7

60.8

72.6

95.7

95% CI

19.8–37.2

70.4–85.6

75.5–86.9

46.1–74.2

58.3–84.1

92.7–97.7

Specificity

Rate (%)

99.1

14.1

68.9

97.9

14.8

61

95% CI

96.9–99.9

9.8–19.4

60.8–76.2

95.6–99.2

10.9–19.4

44.5–75.8

PPV

Rate (%)

93.9

33.7

76.85

83.8

13

94.7

95% CI

79–98.5

31.3–36.1

72.2–80.9

69.4–92.2

11.1–15.1

92.5–96.4

NPV

Rate (%)

74.1

54.4

74.8

93.4

75.4

65.8

95% CI

71.8–76.3

42.7–65.7

68.4–80.3

91–95.3

64.5–83.9

51.7–77.5

Accuracy

Rate (%)

76

37.1

76

92.4

23.4

91.2

95% CI

71.1–80.5

32–42.5

71.1–80.5

89.1–95

19–28.2

88–94.3