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Table 3 Serial CSF testing (Table 3)

From: Successful treatment of multiple intracerebral aspergillosis with voriconazole alone in an Egyptian diabetic patient with autoimmune hemolytic anemia

On admission

  

Reference:

 Aspect

Semi turbid

 

Clear aspect

 Color

Yellow

 

Colorless

 Protein

154

mg/dl

15–40

 Glucose

70

mg/dl

50–80

 WBCs count

400

/cmm

0–5 (lymphocytes)

 PNL

60

%

0

 Lymphocytes

40

%

Negative for bacteria

 Gram stain

No organism detected

 

Negative for acid-fast bacilli

 Zehil Nelseen stain

No acid-fast bacilli

  

 PCR for TB

Negative

 

Negative

 Fungal culture

Negative

 

Negative

 CSF HSV PCR

Negative

 

Negative

 Culture for bacteria

No growth

 

No growth

 Galactomannan test

Positive

 

Negative

After 3 days:

 

Cells/cc

 

 Cells

300 (many RBCs)

%

0–5 (lymphocytes)

 Neutrophils

60

%

Zero

 Lymphocytes

40

 

0–5

 Pathogens:

   

  Gram stain

No bacteria

 

No bacteria

  Zeihl Nelseen stain

No acid-fast bacilli

mg/dl

No acid-fast bacilli

  Glucose

80

mg/dl

50–80

  Proteins

121

 

15–40

One week later:

 

Cells/cc

 

 Cells

50

%

0–5

 Neutrophils

10

%

0

 Lymphocytes

90

 

0–5

 Pathogens:

   

  Gram stain

No bacteria

 

No bacteria

  Zehil Nelseen stain

No acid-fast bacilli

mg/dl

No acid-fast bacilli

  Glucose

104

mg/dl

50–80

  Protein

52

 

15–40

Two weeks later

   

 Aspect

Clear

 

Clear

 Color

Colorless

Cell/cc

Colorless

 Cell count

35

%

0–5 lymphocytes

 Neutrophils

20

%

0

 Lymphocytes

80

mg/dl

0–5

 Glucose

118

mg/dl

50–80

 Proteins

35

 

15–40

 Pathogens:

   

  Gram stain

No bacteria

 

No bacteria

  Zeihl Nelseen stain

No acid-fast bacilli

 

No acid-fast bacilli

Before discharge (after one month)

 

Cell/cc

 

 Cell count

20

%

0–5(lymphocytes)

 Neutrophils

40

%

0

 Lymphocytes

60

 

0–5

 Pathogens:

   

  Gram stain

No bacteria

 

No bacteria

  Zehil Nelseen

No acid-fast bacilli

mg/dl

No acid-fast bacilli

  Glucose

122

mg/dl

50–80

  Protein

42

 

15–40