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Table 3 The relationship between DANCR expression and different parameters in AML

From: Assessing the expression of differentiation antagonizing non-protein coding RNA (DANCR) in newly diagnosed Egyptian acute myeloid leukemia patients

 

lncRNA DANCR

  

Variable

Low (≤ 0.64)

(n = 30)

High (> 0.64)

(n = 30)

χ2

p

No

%

No

%

  

Age (/years)

 18 – 30

9

30.0

9

30.0

0.889

0.641

  > 30 – 45

14

46.7

11

36.7

  > 45 – 65

7

23.3

10

33.3

Sex

 Male

12

40.0

12

40.0

0.000

1.000

 Female

18

60.0

18

60.0

FAB subtypes

 M0

0

0.0

2

6.7

15.510*

MCp = 0.001*

 M1

4

13.3

16

53.3

 M2

2

6.7

2

6.7

 M4

8

26.7

5

16.7

 M5

16

53.3

5

16.7

Cytogenetics

 Normal

16

53.3

12

40.0

1.071

0.301

 Abnormal cytogenetics

6

20.0

7

23.3

0.098

0.754

 Undefined a

8

26.7

11

36.7

0.693

0.405

Response to treatment

 Partial remission

2

6.7

1

3.3

0.351

FEp = 1.000

 Complete remission

5

16.7

7

23.3

0.417

0.519

 Refractory

11

36.7

8

26.7

0.693

0.405

 Died

9

30.0

10

33.3

0.077

0.781

 Lost in Follow-up

3

10.0

4

13.3

0.162

FEp = 1.000

  1. χ2 Chi square test, MC Monte Carlo, FE Fisher Exact
  2. p: p value for comparing between Low (≤ 0.64) and High (> 0.64)
  3. a AML patients with no metaphase on karyotyping
  4. *: Statistically significant at p ≤ 0.05