Table 5 Correlation of serum irisin with other studied parameters among cases with DM only, T2DM with DN, and T2DM with CVD groups

Serum irisin (ng/dl)

–

–

–

–

–

–

Age years

0.255

0.308

0.634

0.003

0.067

0.779

BMI (kg/m²)

 − 0.560

0.016

 − 0.502

0.024

 − 0.243

0.301

Duration (years)

0.068

0.789

 − 0.227

0.336

 − 0.402

0.079

Systolic BP (mmHg)

 − 0.113

0.656

0.147

0.536

0.302

0.196

Diastolic BP (mmHg)

 − 0.442

0.066

0.152

0.524

0.028

0.908

FBG (mg/dl)

0.222

0.377

 − 0.018

0.939

0.107

0.653

2hPP (mg/dl)

0.089

0.724

0.200

0.398

0.227

0.337

HbA1C%

0.501

0.034

0.085

0.721

0.097

0.685

Urea (mg/dl)

0.333

0.177

 − 0.049

0.839

 − 0.103

0.664

Creatinine (mg/dl)

0.219

0.383

 − 0.115

0.629

 − 0.034

0.886

A/C (mg)

 − 0.103

0.684

 − 0.503

0.024

 − 0.181

0.446

e-GFR (ml/min/1.73 m²)

 − 0.137

0.587

0.236

0.316

0.485

0.030

LDL/cholesterol (mg/dl)

0.082

0.746

0.006

0.980

 − 0.612

0.004

TG (mg/dl)

0.222

0.376

 − 0.468

0.037

 − 0.658

0.002

Total cholesterol (mg/dl)

HDL (mg/dl)

 − 0.096

 − 0.092

0.706

0.717

 − 0.418

 − 0.055

0.067

0.819

 − 0.693

0.283

0.001

0.226