Table 4 Relation of serum irisin with other parameters among the whole patients, DM only, T2DM with DN, and T2DM with CVD groups

Gender

Female

0.92 ± 0.22

0.007

0.91 ± 0.29

0.007

0.88 ± 0.12

0.033

0.99 ± 0.25

0.620

Male

1.11 ± 0.3

1.24 ± 0.07

1.04 ± 0.19

1.08 ± 0.41

Insulin

No

1 ± 0.23

0.569

1.08 ± 0.27

0.518

0.95 ± 0.17

0.781

0.85 ± 0.17

0.227

Yes

1.04 ± 0.34

0.94 ± 0.41

0.93 ± 0.19

1.1 ± 0.38

OHG

No

1.04 ± 0.35

0.662

0.94 ± 0.41

0.518

0.85 ± 0.19

0.208

1.1 ± 0.38

0.227

Yes

1 ± 0.22

1.08 ± 0.27

0.97 ± 0.16

0.85 ± 0.17

Comorbidity

No

1.01 ± 0.32

0.846

1.05 ± 0.29

0.762

0.91 ± 0.09

0.433

1.05 ± 0.45

0.972

HTN

1.02 ± 0.21

1.09 ± 0.26

0.98 ± 0.22

1.04 ± 0.17

A/C groups

Normal

1.05 ± 0.32

0.217

1 ± 0.18

0.090

Microalbuminuria

1 ± 0.18

0.87 ± 0.13

Macroalbuminuria

0.87 ± 0.13

0.92 ± 0.02

eGFR groups

G1

1.03 ± 0.14

0.207

1.15 ± 0.15

0.251

1.06 ± 0.19

0.021

0.99 ± 0

0.161

G2

1.07 ± 0.32

0.98 ± 0.31

0.76 ± 0.08

1.15 ± 0.37

G3a

0.87 ± 0.27

1.29 ± 0

0.93 ± 0.09

0.79 ± 0.26