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Table 2 Comparison between control and patients’ groups regarding clinical and laboratory data

From: Association between irisin and vascular complications of type 2 diabetic patients: a prospective case–control study

 

Control group

No. 30

Patients group

No. 60

p-value

DM only

No. 20

Diabetic nephropathy

No. 20

DM + cardiovascular

No. 20

p-value

Systolic BP (mmHg)

Mean ± SD

109.00 ± 9.14

128.83 ± 14.39

 < 0.0001

125.00 ± 11.47

133.00 ± 17.20

128.50 ± 13.48

 < 0.0001

Diastolic BP (mmHg)

Mean ± SD

70.00 ± 6.43

81.17 ± 8.65

 < 0.0001

81.50 ± 6.71

82.00 ± 11.96

80.00 ± 6.49

 < 0.0001

FBG (mg/dl)

Mean ± SD

86.00 ± 10.98

137.20 ± 46.35

 < 0.0001

116.95 ± 31.29

156.60 ± 39.42

138.05 ± 57.54

 < 0.0001

2hPP (mg/dl)

Mean ± SD

122.00 ± 8.73

241.52 ± 82.38

0.0001

202.75 ± 71.12

274.10 ± 55.56

247.70 ± 100.95

 < 0.0001

HbA1C%

Mean ± SD

5.35 ± 0.14

8.15 ± 1.71

 < 0.0001

7.43 ± 1.49

8.93 ± 1.16

8.11 ± 2.08

 < 0.0001

Urea (mg /dl)

Mean ± SD

21.73 ± 4.39

39.87 ± 15.04

 < 0.0001

28.30 ± 4.62

54.30 ± 14.03

37.00 ± 10.74

 < 0.0001

Creatinine (mg/dl)

Mean ± SD

0.67 ± 0.10

1.04 ± 0.24

 < 0.0001

0.95 ± 0.21

1.13 ± 0.30

1.05 ± 0.17

 < 0.0001

A/C (mg)

Median

7 (4 − 9)

16 (9.3 − 168)

 < 0.0001

12.5 (8–19)

201.5 (168–411)

11.5 (8–13)

 < 0.0001

e-GFR (ml/min/1.73 m2)

Mean ± SD

121.13 ± 17.70

73.32 ± 19.06

 < 0.0001

81.50 ± 19.64

67.50 ± 21.86

70.95 ± 12.34

 < 0.0001

LDL/cholesterol (mg/dl)

Mean ± SD

74.87 ± 11.38

118.15 ± 32.95

 < 0.0001

114.45 ± 20.08

115.00 ± 37.79

125.00 ± 38.28

 < 0.0001

TG (mg/dl)

Mean ± SD

84.00 ± 29.17

122.78 ± 36.33

 < 0.0001

129.15 ± 36.70

133.50 ± 25.25

105.70 ± 40.55

 < 0.0001

Total cholesterol (mg/dl)

Mean ± SD

123.73 ± 40.66

185.98 ± 47.38

 < 0.0001

173.95 ± 44.73

196.30 ± 37.57

187.70 ± 57.36

 < 0.0001

HDL (mg/dl)

Mean ± SD

69.6 ± 6.1

52.72 ± 11.65

 < 0.0001

56.00 ± 11.08

48.30 ± 12.34

53.85 ± 10.98

 < 0.0001

  1. Data are presented by mean ± standard deviation (SD), median (interquartile 1–3), numbers, percent (%), P-value < 0.05 is significant, P-value < 0.0001 is highly significant. P1, control vs DM; P2, control vs DN; P3, control vs DM + cardiovascular; P4, DM vs DN; P5, DM vs DM + cardiovascular; P6, DN vs DM + cardiovascular