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Table 1 Summary of different biomarkers

From: Different novel biomarkers involved in diagnosing hypothyroidism

Biomarkers

Variables

Tests

Action

1. Thyroid profile

T3 (nmol/l)

All tests confirm the changes in hormones affecting normal thyroid function

T4 (nmol/l)

TSH (mlU/L)

FT3 (ρmol/l)

FT4 (ρmol/l)

T3 resin uptake

Free T4 index

T4-binding globulin

Anti-TPO

Radioactive iodine uptake

2. Lipid profile

TC (mg/dl)

Reduced activity of HMG-CoA reductase shows the changes in cholesterol levels in the body due to hypothyroidism

TAG (mg/dl)

HDL-C (mg/dl)

TC/HDL-C

TAG/HDL-C

3. Cytokines

IL-6

Confirming changes in autoimmunity of thyroid

TNF-α

Visfatin (ng/ml)

Leptin (ng/ml)

4. Others

Hb

Hemoglobine level

Iron and zinc

For iron and zinc deficiency

Ferritin

For iron

TIBC

For iron