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Table 2 Pharmacokinetics of DOACs

From: An update on applications and limitations of direct oral anticoagulants

Drug

Half life

Time to elapse 5 half lives

Apixaban

8–15 h

1.5–3 days after last dose

Rivaroxaban

5–9 h

1–2 days after last dose

Edoxaban

6–11 h

1.3–2 days after last dose

Dabigatran

12–17 h

2.5–3.5 days after last dose