Table 1 Clinical trials of JAK inhibitors for myelofibrosis

Ruxolitinib

III (COMFORT-2)

III (COMFORT-1)

[15, 16]

Fedratinib

II (JAKARTA-2)

III (JAKARTA)

[17, 18]

Momelotinib

III (SIMPLIFY-1)

III (SIMPLIFY-2)

[19, 20]

Pacritinib

II (PERSIST-1)

III (PERSIST-2)

[21, 22]

Gandotinib

II

[23]

Ilginatinib

I

[24]

Itacitinib

II

[25]

Lestaurtinib

II

[26]