Table 6 The curve of receiver operating characteristic (ROC) of the studied indices for optimum cutoff points in diagnosing iron deficiency anemia (compared to healthy control)
Indices | Cutoff | AUC | 95% CI | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Youden index (%) | p-value |
|---|---|---|---|---|---|---|---|---|---|
RDWI | > 240.29 | 0.857 | (0.772, 0.919) | 81.63 | 80 | 80 | 81.6 | 61.63 | < 0.001* |
ML_I | > 16.73 | 0.634 | (0.531, 0.728) | 65.31 | 64 | 64 | 65.3 | 29.31 | 0.018* |
GK | > 84.74 | 0.550 | (0.447, 0.650) | 24.49 | 96 | 85.7 | 56.5 | 20.49 | 0.398 |
EF | ≤ 1.4 | 0.511 | (0.409, 0.613) | 12.24 | 98 | 85.7 | 53.3 | 10.24 | 0.851 |
SL | ≤ 1642.5 | 0.989 | (0.944, 1) | 95.92 | 100 | 92.2 | 95.8 | 95.92 | < 0.001* |
SI | > 5.66 | 0.519 | (0.417, 0.621) | 44.90 | 78 | 66.7 | 59.1 | 22.90 | 0.745 |
RI | > 3.04 | 0.964 | (0.906, 0.991) | 85.71 | 100 | 100 | 87.7 | 85.71 | < 0.001* |
EI | ≤ 36.3 | 0.592 | (0.489, 0.690) | 83.67 | 36 | 56.2 | 69.2 | 19.67 | 0.107 |
Sir_I | ≤ 38.1 | 0.787 | (0.693, 0.863) | 85.71 | 62 | 68.9 | 81.6 | 47.71 | < 0.001* |
HH | > 22.38 | 0.891 | (0.812, 0.945) | 77.55 | 98 | 97.4 | 81.7 | 75.55 | < 0.001* |