Thyrotoxicosis in Africa: a systematic review and meta-analysis of the clinical presentation

The Egyptian Journal of Internal Medicine

Table 11 The pooled frequencies of the signs of thyrotoxicosis

Signs	Frequency (%)	95% CI	p	I² (%)	Q statistic	LFK index
Goiter	88	87–90	<0.0001	97	1193	−8.31
Thyroid bruit	39	25–54	<0.0001	91	53.2	−3.32
Sweaty palms	54	39–69	<0.0001	98	391	0.93
Onycholysis	40	24–64	<0.0001	99	97	–
Pretibial myxedema	7	4–10	<0.0001	91	106	6.57
Tachycardia	67	62–70	<0.0001	99	4361	−8.7
Atrial fibrillation	9	6–12	<0.0001	88	113	4.38
Hand tremor	49	41–58	<0.0001	100	12,036	−8.88
Proximal myopathy	29	15–46	<0.0001	97	181	0.59
Exophthalmos	49	36–41	<0.0001	99	2085	−1.67
Lid retraction	19	1–48	<0.0001	99	515	0.2
Lid lag	17	0–43	<0.0001	99	407	0.01
Other eye signs	49	35–62	<0.0001	97	454	−0.38