Immune-mediated adverse events post-COVID vaccination and types of vaccines: a systematic review and meta-analysis

ElSawi, Hind A.; Elborollosy, Ahmed

doi:10.1186/s43162-022-00129-5

The Egyptian Journal of Internal Medicine

Table 5 Studies that showed comorbidities of involved vaccinated patients

From: Immune-mediated adverse events post-COVID vaccination and types of vaccines: a systematic review and meta-analysis

Author	Name of vaccine	Type of study	Comorbidity	Adverse event
Ng XL et al. 2021 [35]	66 Pfizer-BioNTech /7 Oxford/AstraZeneca /1BBIBP Corv	Retrospective (observational study)	Diabetes, rheumatolgical disorders	Acute macular neuroretinopathy/facial palsy
Hal F et al. 2021 [31]	Oxford/AstraZeneca	Case report	Cancer breast	Erythema nodosum
Biswas A et al. 2021 [21]	Oxford/AstraZeneca	Case report	Non-syndromic retinitis pigmentosa	Guillian Barre syndrome (GBS)
Boonyawat K et al. 2022 [8]	Oxford/AstraZeneca	Case reports	Diabetes, hypertension, and hyperlipidemia	Thrombotic thrombocytopenic purpura (TTP)
Nasuelli NA et al. 2021 [25]	Oxford/AstraZeneca	Case report	Hypertension and hyperuricemia	Acute demyelinating polyradiculopathy
Takata J et al. 2021 [27]	Oxford/AstraZeneca	Case report	Non-syndromic retinitis pigmentosa	Acute disseminated encephalomyelitis
Greinacher A et al. 2021 [10]	Oxford/AstraZeneca	Case series	Von Willebrand disease, anti-cardiolipin antibodies, and factor V Leiden	Thrombotic thrombocytopenic purpura (TTP)/ disseminated intravascular coagulopathy (DIC)
Hasan T et al. 2021 [22]	Oxford/AstraZeneca	Case report	Bronchiectasis, asthma, osteoporosis and migraine.	Guillian Barre syndrome (GBS)
Klomjit N et al. 2021 [29]	6 Pfizer-BioNTech/7 Moderna		Cancer/diabetes/autoimmune	Renal complications
Akinosoglou K et al. 2021 [1]	Pfizer-BioNTech	Case report	Cutaneous small cell vasculitis	Cutaneous vasculitis
Fueyo-Rodriguez O et al. 2021 [16]	Pfizer-BioNTech	Case report	Hypo thyroidism, hypertension and pre-diabetes	Idiopathic thrombocytopenic purpura (ITP)
Vogrig A et al. 2021 [28]	Pfizer-BioNTech	Case report	History of post-infectious rhombencephalitis	Acute disseminated encephalomyelitis
Innao V et al. 2022 [11]	Pfizer-BioNTech	Case reports	Nodular sclerosis classical Hodgkin lymphoma (NScHL), in stage VI B disease	Thrombotic thrombocytopenic purpura (TTP)
Bouattour N et al. 2022 [23]	Pfizer-BioNTech	Case report	Type II diabetes	Guillian Barre Syndrome
Malayala SV et al. 2021 [17]	Pfizer-BioNTech	Case report	Rheumatoid arthritis, scleroderma, mixed connective tissue disease, hypertension, cardiac disease, and osteopenia	Idiopathic thrombocytopenic purpura (ITP)
Jasaraj RB et al. 2021 [18]	Pfizer-BioNTech	Case report	Hypertension, type 2 diabetes mellitus, hypothyroidism, depression, vitamin B12 deficiency,	Idiopathic thrombocytopenic purpura (ITP)
Nishiguchi Y et al. 2021 [26]	Pfizer-BioNTech	Case report	Diabetes mellitus and diabetic ophthalmoplegia	Miller Fisher syndrome
Helms JM et al. 2021 [19]	Moderna	Case report	Hypertension, gout, hyperlipidemia, and non-ischemic cardiomyopathy	Idiopathic thrombocytopenic purpura (ITP)
Sekar A et al. 2021 [30]	Moderna	Case report	Hypertension	Renal complication
Sung JG et al.2021 [12]	Moderna	Case reports	Hypertension, hyperlipidemia, diabetes mellitus, coronary artery disease	Acute myocardial infarction

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