Skip to main content

Table 3 Relationship between MAP, eGFR, and other clinical variables

From: Incidence, demographic, biochemical, and clinicopathological profile of primary IgAN in a tertiary care center from Northern India

Characteristic

MAP (mmHg) No. of patients

eGFR (ml/min/1.73m2) No of patients

Proteinuria in gram/day No of patients

<104 39

≥104

67

p value

>59.9

55

30–59.9

29

<30

22

P value

<1

19

1–2.99

57

>3

30

p value

Age mean±SD

27.74±7.86

33.48±12.91

ns

28.82±11.4

32±9.25

36.91±13.25

0.017b

31.21±9.85

33.28±11.93

27.83±11.52

0.04c

Gender male: female (ratio)

23:16 (1.44:1)

41:26 (1.56:1)

ns

13:9 (1.44:1)

14:15 (0.9:1)

37:18 (2.05:1)

ns

13:6 (2.1:1)

32:25 (1.28:1)

19/11 (1.72:1)

ns

Systolic BP mmHg mean±SD

113.44±9.53

151.67±12.28

<0.001

125.71±18.62

141.59±16.02

162.09±9.98

0.007a

0.001b,c

129.68±23.44

137.19±21.29

143.40±20.32

ns

Diastolic BP mmHg mean±SD

72.10±7.92

92.85±3.98

<0.001

79.35±12.03

88.38±6.58

95.73±4.33

0.01a,c

0.001b

77.79±14.23

85.88±10.43

88.67±9.96

0.012b

MAP in mmHg mean±SD

85.85±7.84

112.51±5.91

<0.001

94.96±14.02

105.86±9.05

94.96±14.02

0.013a

0.001b,c

95.11±16.94

103±13.62

106.93±13.09

0.031b

Mean (SD) 24-h urine protein

1.95 (1.21)

2.53 (1.36)

0.01

2.47±1.54

2.16±1.06

2.13±1.08

ns

0.79±0.21

1.90±0.48

4.08±0.95

0.001

Serum creatinine mg/dl mean±SD

1.11 (0.31)

2.0 (0.88)

<0.001

1.07±0.24

1.86±0.93

2.92±0.61

0.001a,b 0.012c

1.86±1.03

1.63±0.79

1.62±0.81

ns

eGFR ml/min/1.73m2 mean±SD

86.03±24.45

50.27±27.92

<0.001

89±20.43

44.10±10.12

24.45±4.60

0.001a,b 0.010c

62.16±36.07

61.96±30.22

66.9±33.21

ns

  1. SD standard deviation, MAP mean arterial pressure, BP blood pressure, eGFR estimated glomerular filtration rate (calculated using CKD-EPI chronic kidney disease epidemiology collaboration formula), ns not significant
  2. aColumns 1 and 2
  3. bColumns 1 and 3
  4. cColumns 2 and 3