Effect of different direct-acting antiviral regimens for treatment of nondiabetic hepatitis C virus–infected Egyptian patients on insulin resistance and sensitivity

The Egyptian Journal of Internal Medicine

Table 4 Insulin sensitivity before and after SVR at 12 weeks among patients in group A

Insulin sensitivity/resistance index	Mean	SD	t^a	P value
HOMA-IR before	3.19	1.35	8.28	< 0.001
HOMA-IR after	2.17	.96	8.28	< 0.001
QUICKI before	.33	.02	5.78	< 0.001
QUICKI after	.35	.03	5.78	< 0.001
Matsuda index before	5.57	2.03	3.37	0.003
Matsuda index after	6.57	2.31	3.37	0.003

^aPaired samples t test
The HOMA-IR, QUICKI, and Matsuda indices were highly significant in group A before and after treatment (P < 0.001)