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Table 5 Prognostic scores for the 3 ACLF degrees in both ward and ICU patients

From: Clinical profile and outcome among patients with acute-on-chronic liver failure admitted in the intensive care unit

 

ACLF1

ACLF2

ACLF3

P-value

Ward

ICU

Ward

ICU

Ward

ICU

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

CTP Score

      

0.0003

Child A

1(5%)

0(0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

Child B

4 (20%)

1 (5%)

1 (5%)

1 (5%)

0 (0%)

0 (0%)

Child C

5(25%)

9(45%)

9 (45%)

9 (45%)

10 (50%)

10 (50%)

P-value

0.14

1.0

1.0

 
 

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

 

MELD

21.5 ± (3.5)

21.9 ± (3.7)

28.2 ± (6.3)

22.5 ± (4.4)

35.1 ± (7.7)

29.1 ± (6.5)

8.2×10-5

P-value

0.81

0.043

0.076

 

MELD Na+

25.0 ± (3.1)

24.2 ± (3.6)

31.1 ± (4.9)

25.6 ± (4.6)

35.4 ± (7.0)

29.9 ± (7.0)

0.001

P-value

0.598

0.119

0.129

 

APACHE

12.1 ± (4.2)

13.6 ± (4.2)

16.1 ± (2.2)

19.8 ± (5.3)

18.3 ± (3.0)

21.5 ± (3.7)

3.4×10-6

P-value

0.433

0.066

0.0495

 

SOFA

6.9 ± (1.7)

8.4 ± (1.9)

9.5 ± (1.4)

8.7 ± (1.6)

11.0 ± (2.5)

13.2 ± (3.0)

3.5×10-6

P-value

0.081

0.25

0.093

 

CLIF SOFA

6.0 ± (1.3)

6.8 ± (1.4)

8.3 ± (1.3)

8.2 ± (1.4)

11.2 ± (1.7)

13.0 ± (2.4)

1.4×10-9

P-value

0.21

0.872

0.086

 

CLIF. OF

8.9 ± (0.6)

9.2 ± (0.8)

10.7 ± (0.5)

10.3 ± (0.5)

13.6 ± (1.5)

14.6 ± (2.2)

2.3×10-11

P-value

0.335

0.089

0.256

 

CLIF C ACLF

45.5 ± (6.3)

46.1 ± (7.1)

54.3 ± (4.9)

54.7 ± (5.7)

65.5 ± (5.0)

68.7 ± (6.5)

1.6×10-15

P-value

0.844

0.868

0.238

 
  1. Table 5 shows a significant increase in all prognostic scores with increasing the grade of ACLF in all patients in the ward and ICU and also showed a non-significant difference between ACLF subgroups in the ward compared to the ICU group except for APACHE that showed a significant increase in subgroup ACLF3 in the ICU compared to subgroup ACLF3 in the ward