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Table 3 Biochemical profile for the 3 ACLF degrees in the 2 studied groups

From: Clinical profile and outcome among patients with acute-on-chronic liver failure admitted in the intensive care unit

 

ACLF1

ACLF2

ACLF3

Ward

ICU

P-value

Ward

ICU

P-value

Ward

ICU

P-value

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Hb. (g/dl)

8.6 ± (0.8)

9.1 ± (1.7)

0.21

9.5 ± (1.5)

9.7 ± (1.4)

0.78

10.0 ± (1.9)

10.8 ± (2.2)

0.27

Hematocrit (%)

26.8 ± (1.8)

29.4 ± (5.3)

0.13

30.1 ± (4.2)

28.8 ± (4.0)

0.48

30.5 ± (6.6)

32.0 ± (8.1)

0.41

WBCs total(*109/L)

8.4 ± (5.9)

10.2 ± (6.2)

0.76

9.5 ± (5.0)

16.5 ± (7.1)

0.12

15.7 ± (7.6)

16.6 ± (6.9)

0.785

Platelets (*109/L)

116.3 ± (72.5)

89.2 ± (52.4)

0.48

71.6 ± (35.5)

118.6 ± (37.1)

0.41

99.3 ± (70.7)

110.7 ± (37.0)

0.66

AST (U/L)

84.2 ± (60.2)

126.2 ± (260.8)

0.27

103.1 ± (63.2)

95.7 ± (95.2)

0.315

229.4 ± (173.6)

174.2 ± (137.3)

0.52

ALT (U/L)

36.3 ± (14.6)

72.5 ± (91.3)

0.79

67.8 ± (65.4)

52.1 ± (43.4)

0.325

119.6 ± (105.1)

80.3 ± (61.9)

0.545

Bilirubin (mg/dl)

3.5 ± (3.5)

3.1 ± (2.4)

1.0

7.0 ± (7.8)

2.9 ± (1.2)

0.55

12.1 ± (8.5)

9.2 ± (8.2)

0.38

INR

1.4 ± (0.3)

1.6 ± (0.3)

0.30

2.0 ± (0.6)

1.6 ± (0.3)

0.15

2.5 ± (0.7)

2.1 ± (0.6)

0.146

Creatinine (mg/dl)

2.5 ± (0.9)

4.5 ± (0.9)

0.62

2.6 ± (0.9)

2.2 ± (0.9)

0.404

3.5 ± (1.1)

2.8 ± (1.8)

0.14

CRP (mg/L)

54.2 ± (24.2)

77.0 ± (26.1)

0.06

76.6 ± (25.1)

91.2 ± (15.2)

0.13

72.2 ± (25.5)

95.2 ± (37.9)

0.355

Albumin (g/L)

2.8 ± (0.8)

2.2 ± (0.4)

0.055

2.5 ± (0.4)

2.4 ± (0.4)

0.36

2.4 ± (0.7)

2.2 ± (0.5)

0.595

Pao2

70.5 ± (23.0)

79.5 ± (62.5)

0.427

51.9 ± (13.6)

49.6 ± (12.7)

0.97

41.8 ± (9.8)

46.0 ± ( 14.2)

0.65

Pao2/Fio2

311.9 ± (105.3)

303.4 ± (82.2)

0.85

246.1 ± (65.9)

217.9 ± (32.6)

0.73

198.9 ± (46.7)

177.6 ± (53.3)

0.35

PaCo2

36.5 ± (6.2)

41.0 ± (16.7)

0.88

34.0 ± (7.6)

37.4 ± (6.0)

0.28

39.2 ± (4.4)

33.7 ± (8.6)

0.096

Na+ (meq/L)

130.0 ± (6.9)

132.1 ± (4.0)

0.565

131.8 ± (8.5)

132.3 ± (9.4)

0.76

128.6 ± (6.3)

133.4 ± (10.9)

0.40

K+ (meq/L)

3.7 ± (0.7)

3.8 ± (0.7)

0.67

4.0 ± (0.9)

3.7 ± ( 0.8)

0.42

3.4 ± (0.5)

3.8 ± ( 0.8)

0.19

  1. Table 3 shows a non-significant difference between 3 ACLF subtypes in the ward compared to 3 ACLF subtypes in ICU as regards the biochemical profile