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Table 2 Clinical profile for the 3 ACLF degrees

From: Clinical profile and outcome among patients with acute-on-chronic liver failure admitted in the intensive care unit

 

ACLF1

ACLF2

ACLF3

Ward

ICU

P-value

Ward

ICU

P-value

Ward

ICU

P-value

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Temperature

37.8 ± (0.5)

37.9 ± (0.5)

0.457

38.0 ± (0.8)

38.4 ± (0.5)

0.277

37.9 ± (0.6)

38.0 ± (0.8)

0.927

Pulse (beats/min)

85.7 ± (10.6)

90.2 ± (6.8)

0.107

91.9 ± (13.3)

94.1 ± (14.1)

0.724

94.8 ± (14.3)

96.1 ± (15.9)

0.849

Respiratory rate (times/min)

18.6 ± (6.1)

16.6 ± (2.3)

0.937

20.1 ± (7.9)

21.3 ± (4.6)

0.25

17.1 ± (4.6)

25.6 ± (10.7)

0.046

GCS

14.1 ± (1.2)

11.9 ± (1.7)

0.006

12.9 ± (1.4)

10.1 ± (1.2)

0.0001

12.7 ± (1.6)

9.1 ± (4.0)

0.023

 

N (%)

N (%)

0.046

N (%)

N (%)

0.001

N (%)

N (%)

0.003

Hepatic encephalopathy

        

Grade0

2 (100%)

0 (0%)

1(100%)

0 (0%)

0 (0%)

0 (0%)

Grade1

3 (100%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

Grade2

4 (44.4%)

5 (55.6%)

8 (88.9%)

1 (11.1%)

7 (100.0%)

0 (0.0%)

Grade3or4

1 (16.7%)

5 (83.3%)

1 (10.0%)

9 (90.0%)

3 (23.1%)

10 (76.9%)

Ascites

  

0.322

  

1.0

  

0.65

Mild

2 (100%)

0 (0%)

1 (100%)

0 (0%)

1 (100%)

0 (0.0%)

Moderate

1 (25.0%)

3 (75.0%)

1 (50.0%)

1 (50.0%)

4 (57.1%)

3 (42.9%)

marked

7 (50.0%)

7 (50.0%)

8 (47.1%)

9 (52.9%)

5 (41.7%)

7 (58.3%)

  1. Table 2 shows a significant increase in hepatic encephalopathy and a significant decrease in GCS in subgroups ACLF1, 2, 3 in the ICU compared to subgroups ACLF1, 2, 3 in the ward. In addition, it showed a significant increase in the respiratory rate in ACLF3 in the ICU compared to ACLF3 in the ward