Table 5 Association of PTX3 and PVT1 gene polymorphism in T2DM patients with and without DKD
Gene (rsID) | Models | T2DM patients with DKD | T2DM patients without DKD | Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|
PTX3 rs2305619 (A/G) | Co-dominant model | ||||
 AA | 72 | 70 | Ref | - | |
 AG | 25 | 34 | 0.67 (0.37–1.21) | 0.18 | |
 GG | 43 | 36 | 1.28 (0.75–2.15) | 0.35 | |
Dominant model | |||||
 AG+GG vs AA | - | - | 0.96 (0.56–1.62) | 0.89 | |
Recessive model | |||||
 GG vs AA+AG | - | - | 0.58 (0.28–1.20) | 0.15 | |
Allelic model | |||||
 A | 188 | 195 | Ref | - | |
 G | 92 | 85 | 0.89 (0.62–1.27) | 0.52 | |
PVT1 rs2648875 (G/A) | Co-dominant model | ||||
 GG | 89 | 85 | Ref | - | |
 GA | 43 | 40 | 1.41 (0.79–2.50) | 0.24 | |
 AA | 8 | 15 | 1.10 (0.66–1.85) | 0.69 | |
Dominant model | |||||
 GA+AA vs GG | - | - | 1.16 (0.67–1.92) | 0.58 | |
Recessive model | |||||
 AA vs GG+GA | - | - | 1.42 (0.62–3.21) | 0.40 | |
Allelic model | |||||
 G | 184 | 186 | Ref | - | |
 A | 96 | 94 | 0.96 (0.68–1.37) | 0.85 | |