Table 4 Association of PTX3 and PVT1 gene polymorphism in T2DM patients with DKD and controls
Gene (rsID) | Models | T2DM patients with DKD | Controls | Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|
PTX3 rs2305619 (A/G) | Co-dominant model | ||||
 AA | 75 | 85 | Ref | - | |
 AG | 29 | 35 | 1.27 (0.72–2.23) | 0.39 | |
 GG | 36 | 20 | 2.07 (1.13–3.80) | 0.01* | |
Dominant model | |||||
 AG+GG vs AA | - | - | 1.16 (0.67–2.01) | 0.58 | |
Recessive model | |||||
 GG vs AA+AG | - | - | 0.22 (0.08–0.59) | 0.002* | |
Allelic model | |||||
 A | 191 | 216 | Ref | - | |
 G | 89 | 64 | 0.63 (0.43.0–0.92) | 0.01* | |
PVT1 rs2648875 (G/A) | Co-dominant model | ||||
 GG | 77 | 84 | Ref | - | |
 GA | 38 | 36 | 1.07 (0.63–1.83) | 0.78 | |
 AA | 24 | 20 | 1.24 (0.65–2.36) | 0.51 | |
Dominant model | |||||
 GA+AA vs GG | - | - | 1.25 (0.73–2.11) | 0.40 | |
Recessive model | |||||
 AA vs GG+GA | - | - | 0.61 (0.22–1.60) | 0.32 | |
Allelic model | |||||
 G | 194 | 214 | Ref | - | |
 A | 86 | 66 | 0.69 (0.47–1.01) | 0.06 | |