Table 3 Association of PTX3 and PVT1 gene polymorphism in T2DM patients without DKD and controls
Gene (rsID) | Models | T2DM patients without DKD | Controls | Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|
PTX3 rs2305619 (A/G) | Co-dominant model | ||||
 AA | 78 | 86 | Ref | - | |
 AG | 44 | 47 | 0.90 (0.54–1.49) | 0.70 | |
 GG | 18 | 7 | 2.80 (1.13–6.94) | 0.02* | |
Dominant model | |||||
 AG+GG vs AA | - | - | 1.20 (0.70–2.02) | 0.49 | |
Recessive model | |||||
 GG vs AA+AG | - | - | 0.39 (0.14–1.01) | 0.06 | |
Allelic model | |||||
 A | 197 | 211 | Ref | - | |
 G | 83 | 69 | 0.77 (0.53–1.12) | 0.18 | |
PVT1 rs2648875 (G/A) | Co-dominant model | ||||
 GG | 82 | 84 | Ref | - | |
 GA | 39 | 46 | 0.78 (0.47–1.31) | 0.36 | |
 AA | 19 | 10 | 2.04 (0.91–4.56) | 0.08 | |
Dominant model | |||||
 GA+AA vs GG | - | - | 1.07 (0.62–1.82) | 0.78 | |
Recessive model | |||||
 AA vs GG+GA | - | - | 0.42 (0.16–1.10) | 0.07 | |
Allelic model | |||||
 G | 199 | 209 | Ref | - | |
 A | 59 | 69 | 1.11 (0.74–1.65) | 0.59 | |