Characteristics | Control (N = 140) | T2DM patients without DKD (N = 140) | T2DM patients with DKD (N = 140) | †p value | ‡p value | ǂp value |
---|---|---|---|---|---|---|
Gender (male to female ) | 67:73 | 69:71 | 64:76 | 0.78 | 0.49 | 0.68 |
Age (years) | 55.2 ± 5.4 | 57.4 ± 3.1 | 54.2 ± 5.2 | 0.03 | 0.16 | 0.22 |
BMI (Kg/m2) | 24.2 ± 3.2 | 24.0 ± 3.1 | 24 ± 2.9 | 0.64 | 0.63 | 1.00 |
Diabetes duration (years) | - | 12 ± 3.8 | 13.4 ± 4.0 | - | - | 0.009* |
Fasting blood glucose (mg/dL) | 90.2 ± 8.9 | 162.6 ± 9.8 | 154.3 ± 4.3 | 0.001 | 0.001 | 0.001* |
Postprandial glucose (mg/dL) | 119.5 ± 11.2 | 165.6 ± 13 | 172.2 ± 15.4 | 0.001 | 0.001 | 0.001* |
HbA1c (%) | 5.6 ± 1.5 | 7.7 ± 1.6 | 7.9 ± 2.1 | 0.43 | 0.84 | 0.47 |
Protein to creatinine ratio (mg/g) | 33.2 ± 1.3 | 52.1 ± 1.5 | 64.8 ± 4.3 | 0.001 | 0.001 | 0.001* |
Serum creatinine (mg/dL) | 0.9 ± 0.2 | 0.9 ± 0.31 | 2.9 ± 2.6 | 0.57 | 0.001 | 0.001* |
HDL (mg/dl) | 48 ± 14.9 | 46.1 ± 15.4 | 45.1 ± 15.2 | 0.35 | 0.15 | 0.63 |
LDL (mg/dl) | 93.8 ± 32 | 95.3 ± 29.9 | 97.5 ± 28.5 | 0.72 | 0.37 | 0.58 |
eGFR (ml/min) | 131.9 ± 15.1 | 108.1 ± 11.5 | 54.9 ± 12.5 | 0.001 | 0.001 | 0.001* |
SBP (mmHg) | 112 ± 6.5 | 134.0 ± 6.9 | 144.5 ± 4.5 | 0.001 | 0.001 | 0.001* |
DBP (mmHg) | 74.3 ± 5.2 | 91.2 ± 5.3 | 106.7 ± 3.5 | 0.001 | 0.001 | 0.001* |
Smoking | ||||||
 Yes | 56 | 64 | 59 |  |  |  |
 No | 84 | 76 | 81 | 0.21 | 0.63 | 0.44 |