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Table 2 Demographic and clinical characteristics of the study subjects

From: Association between PTX3 and PVT1 genetic polymorphisms and the risk of diabetic kidney disease in type 2 diabetic patients

Characteristics

Control (N = 140)

T2DM patients without DKD (N = 140)

T2DM patients with DKD (N = 140)

†p value

‡p value

Ç‚p value

Gender (male to female )

67:73

69:71

64:76

0.78

0.49

0.68

Age (years)

55.2 ± 5.4

57.4 ± 3.1

54.2 ± 5.2

0.03

0.16

0.22

BMI (Kg/m2)

24.2 ± 3.2

24.0 ± 3.1

24 ± 2.9

0.64

0.63

1.00

Diabetes duration (years)

-

12 ± 3.8

13.4 ± 4.0

-

-

0.009*

Fasting blood glucose (mg/dL)

90.2 ± 8.9

162.6 ± 9.8

154.3 ± 4.3

0.001

0.001

0.001*

Postprandial glucose (mg/dL)

119.5 ± 11.2

165.6 ± 13

172.2 ± 15.4

0.001

0.001

0.001*

HbA1c (%)

5.6 ± 1.5

7.7 ± 1.6

7.9 ± 2.1

0.43

0.84

0.47

Protein to creatinine ratio (mg/g)

33.2 ± 1.3

52.1 ± 1.5

64.8 ± 4.3

0.001

0.001

0.001*

Serum creatinine (mg/dL)

0.9 ± 0.2

0.9 ± 0.31

2.9 ± 2.6

0.57

0.001

0.001*

HDL (mg/dl)

48 ± 14.9

46.1 ± 15.4

45.1 ± 15.2

0.35

0.15

0.63

LDL (mg/dl)

93.8 ± 32

95.3 ± 29.9

97.5 ± 28.5

0.72

0.37

0.58

eGFR (ml/min)

131.9 ± 15.1

108.1 ± 11.5

54.9 ± 12.5

0.001

0.001

0.001*

SBP (mmHg)

112 ± 6.5

134.0 ± 6.9

144.5 ± 4.5

0.001

0.001

0.001*

DBP (mmHg)

74.3 ± 5.2

91.2 ± 5.3

106.7 ± 3.5

0.001

0.001

0.001*

Smoking

 Yes

56

64

59

   

 No

84

76

81

0.21

0.63

0.44

  1. BMI body mass index, HbA1c glycosylated haemoglobin, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure
  2. †Comparison between T2DM patients without DKD group with control group
  3. ‡Comparison between T2DM patients with DKD group with control group
  4. Ç‚Comparison between T2DM patients without and with DKD group
  5. *Statistical significance