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Table 1 Clinical data of SLE patients at the time of enrollment

From: Frequency and risk factors for hydroxychloroquine retinopathy among patients with systemic lupus erythematosus

Clinical parameter

N (%)

Mean

Range

Age (Y)

 

31.24 ± 7.41

18–50

Sex (F/M)

72 (90%)/8 (10%)

  

Hcq therapy

 Duration of HCQ therapy (years)

  

0.3–15

 Daily dose mg/kg

 

4.89± 1.01

2.2–7.1

 Cumulative dose (g)

 

713.67 ± 498.75

36.5 ± 2190

 SLEDAI

  

0–25

 BCVA

 

0.85 ± 0.30

0.1–1/0.16–1

 ESR (mm/h)

  

5–140

 ANA positive (IU/ml)

75 (93.8%)

  

 Ant-DNA positive (U/ml)

49 (61.3%

  

Fundus

 Normal

77 (96.2%)

  

 Bull’s eye

3 (3.8%)

  

Fundus autofluorescent

 Normal

75 (93.8%)

  

 Abnormal (bull’s eye/RPE)

5 (6.3%)

  

Visual field

 Normal

68 (85.0%)

  

 Significant change

9 (11.3%)

  

 Non-reliable

3 (33.8%)

  
  1. SLEDAI Systemic Lupus Erythematosus Disease Activity Index, HCQ hydroxychloroquine, BCVA best-corrected visual acuity, ESR erythrocyte sedimentation rate, FAF fundus autofluorescence, ANA antinuclear antibody, Anti-DNA anti-deoxyribonucleic acid, RPE retinal pigmented epithelium