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Table 1 Comparison of demographic and clinical data among studied groups

From: Matrix metalloproteinase-9 gene polymorphism (-1562 C/T) and its correlation with diabetic nephropathy

 

Control N = 30

Diabetic without nephropathy (DWN) N = 35

Diabetic nephropathy (DN) N = 35

p

Age (years)

55.7 ± 15.2

58.9 ± 8.5

58 ± 12.3

0.541#

Males

13, 43.3%

16, 45.7%

20, 57.1%

0.481È»

Females

17, 56.7%

19, 54.3%

15, 42.9%

    

P1

P2

P3

SBP (mmHg)

114.8 ± 11.2

119.9 ± 7.8

127.3 ± 16.7

0.294Ï„

0.041Ï„

0.033Ï„

DBP(mmHg)

74.2 ± 6.4

76.1 ± 6.9

78.6 ± 9

0.298Ï„

0.122Ï„

0.184Ï„

Hypertension

4, 13.3%

7, 20%

19, 54.3%

0.475È»

0.001È»

0.003È»

FBS (mg/dL)

90 ± 8.3

121.9 ± 28.9

166.5 ± 51

0.014Ï„

< 0.001τ

< 0.001τ

HbA1C (%)

4.2 ± 0.7

6.9 ± 2.2

9.2 ± 2.2

< 0.001τ

< 0.001τ

< 0.001τ

Creatinine (mg/dL)

0.8 ± 0.2

1 ± 0.3

1.5 ± 0.4

0.157Ï„

< 0.001τ

< 0.001τ

ACR (mg/g)

7.4 ± 2.5

13.5 ± 3.8

176.2 ± 54.7

0.723Ï„

< 0.001τ

< 0.001τ

TC (mg/dL)

127.6 ± 12.1

136.8 ± 35.6

163.1 ± 52.9

0.338Ï„

< 0.001τ

0.005Ï„

TG (mg/dL)

107.3 ± 27.5

108.3 ± 34

163.8 ± 50.9

0.961Ï„

0.006Ï„

0.005Ï„

  1. SD standard deviation, P comparison between DN, DWN, and control, p1 comparison between DWN and control, p2 comparison between DN and control, p3 comparison between DWN and DN groups
  2. τStudent’s t test
  3. ȻChi square test
  4. #ANOVA