A novel biomarker of chronic allograft dysfunction in renal transplant recipients (serum calreticulin and CD47)

The Egyptian Journal of Internal Medicine

Table 3 Statistical correlations between serum serum CD47 levels (pg/ml) on the one hand and renal function, high-sensitivity C-reactive protein (hsCRP), urinary alkaline phosphatase, and degree of renal fibrosis on the other hand in renal transplant recipients (RTR) with stable renal function and chronic allograft dysfunction (CAD)

Variables	Serum CD47 (pg/ml)
Variables	RTR with stable renal function (n = 15)		RTR with CAD (n = 15)
	r	P	r	P
Serum creatinine (mg/dl)	0.713	0.003	0.629	0.012
eGFR (ml/min/1.73 m²)	− 0.543	0.037	− 0.461	0.084
Urinary ACR (mg/g)	0.671	0.006	0.266	0.338
hsCRP (mg/l)	0.797	< 0.001	0.680	0.005
Urinary alkaline phosphatase (U/l)	0.529	0.043	0.581	0.023
Renal interstitial fibrosis	–	–	0.692	0.004

eGFR estimated glomerular filtration rate, ACR albumin/creatinine ratio, hsCRP high-sensitivity C-reactive protein, r Spearman correlation coefficient