Table 2 Clinical and laboratory characteristics of patients with MS classified according to thyroid function tests

Age (years)

29.2 ± 4.36

31.6 ± 6.32

0.299

Disease duration/year

6.3 ± 0.96

6.7 ± 0.88

0.215

Number of relapses in the last 2 years

3.3 ± 0.98

3.7 ± 0.87

0.223

Clinical picture of MS

 Sensory

41 (60.2%)

7 (58.3%)

0.580

 Motor

51 (76.4%)

8 (66.7%)

0.430

 Cerebellar

52 (75%)

7 (58.3%)

0.246

 Speech

10 (14.7%)

3 (25%)

0.356

 Visual

51 (75%)

9 (75%)

0.645

FT3 (pg/ml)

1.64 ± 0.585

2. 7 ± 0.758

˂ 0.001*

FT4 (ng/dl)

1.3 ± 0.57

2.5 ± 0.75

˂ 0.001*

TSH (μIU/ml)

6.2 ± 1.5

0.133 ± 0.056

˂ 0.001*

Anti-TPO (IU/ml)

193.3 ± 71.08

32.39 ± 5.76

˂ 0.001*

Anti-TG (IU/ml)

1.9 ± 1.49

1.48 ± 1.35

0.337

WBC count (cell × 10³/μl)

12.3 ± 1.9

15.7 ± 3.4

˂ 0.001*

Hemoglobin (g/dl)

8.6 ± 2.71

8.5 ± 1.56

0.135

Platelet (cell × 10³/μl)

115.8 ± 28.1

34.4 ± 15.1

˂ 0.001*

Neutrophil count (cell × 10³/μl)

9.61 ± 1.091

12.12 ± 2.68

˂ 0.001*

hs-CRP (μg/ml)

4.46 ± 1.53

9.64 ± 2.99

˂ 0.001*

DMDs

 Methylprednisolone

68 (100%)

12 (100%)

–

 Interferon beta-1a

6 (8.8%)

2 (16.7%)

0.346

 Interferon beta-1b

56 (82.3%)

4 (33.3%)

˂ 0.001*

 Fingolimod

4 (5.8%)

8 (66.6%)

˂ 0.001*