Vitamin D in active systemic lupus erythematosus and lupus nephritis: a forgotten player

The Egyptian Journal of Internal Medicine

Table 1 Demographic and laboratory data of SLE patients and control group

Variables	SLE (n = 100)	Control (n = 66)	P value
Age (years)
Mean ± SD	28.30 ± 8.9	25.32 ± 6.98	0.93
Range	(19.0–54.0)	(18.0–51.0)
Sex
Male	12 (12%)	8 (12.12%)	0.99
Female	88 (88%)	58 (87.87)	0.89
Duration of disease
Mean ± SD	4.0 ± 3.2
Range	(0.5–12.0)
ANA
negative	14 (14%)	66 (100%)	0.000*
positive	86 (86%)	0
Anti-dsDNA	2.00 ± 1.57	0.25 ± 0.12	0.000*
C3 (ug/ml)	3.39 ± 2.92	7.06 ± 3.36	0.000*
C4 (ug/ml)	2.48 ± 1.61	4.73 ± 2.34	0.000*
25(OH)D (ng/ml)	3.38 ± 2.55	5.36 ± 2.88	0.002**

Data are presented as mean ± SD (standard deviation) or number (n) and percentage (%). The independent samples t test was used to compare between means of different parameters in SLE patients and controls. Chi-square test was used to analyze the significance between the percentages. P value < 0.05 is considered to be a significant value
ANA anti-nuclear auto-antibodies, Anti dsDNA anti-double strand antibody, C3 complement 3, C4 complement 4, 25(OH)D 25-hydroxyvitamin D
*Statistically significant (P < 0.05)
**Moderately statistically significant (P < 0.01)