The Egyptian Journal of Internal Medicine

Table 2 Comparison between the drug and control groups as regards the biochemical data at baseline and after 6 months

From: Effect of atorvastatin on inflammatory markers in hemodialysis patients

		Groups		t test
		Drug group, mean ± SD	Control group, mean ± SD	t test
		Drug group, mean ± SD	Control group, mean ± SD	t	P value
AST	Baseline	17.879 ± 6.348	17.200 ± 6.469	0.375	0.709
AST	After 6 months	15.242 ± 5.831	15.550 ± 6.219	− 0.182	0.857
ALT	Baseline	15.727 ± 6.458	13.450 ± 5.799	1.292	0.202
ALT	After 6 months	14.061 ± 4.115	13.550 ± 6.452	0.352	0.726
CK-T	Baseline	67.182 ± 32.520	71.350 ± 33.039	− 0.450	0.655
CK-T	After 6 months	69.242 ± 28.306	81.900 ± 33.176	− 1.478	0.145
T. cholesterol	Baseline	177.152 ± 43.952	164.650 ± 56.611	0.899	0.373
T. cholesterol	After 6 months	122.667 ± 30.370	175.800 ± 60.845	− 4.237	< 0.001*
HDL	Baseline	35.030 ± 8.372	37.050 ± 9.827	− 0.797	0.429
HDL	After 6 months	38.909 ± 8.364	37.150 ± 10.205	0.683	0.498
LDL	Baseline	106.182 ± 39.819	93.200 ± 43.397	1.112	0.271
LDL	After 6 months	67.758 ± 22.240	110.000 ± 47.703	− 4.380	< 0.001*
Triglycerides	Baseline	179.939 ± 65.941	171.650 ± 73.992	0.424	0.674
Triglycerides	After 6 months	97.879 ± 39.478	155.800 ± 68.743	− 3.906	< 0.001*
IL-6, pg/ml	Baseline	6.543 ± 4.499	6.800 ± 4.295	− 0.205	0.838
IL-6, pg/ml	After 6 months	6.627 ± 4.214	7.085 ± 3.575	− 0.406	0.687
CRP, mg/l	Baseline	8.989 ± 5.223	9.688 ± 5.000	− 0.480	0.634
CRP, mg/l	After 6 months	4.850 ± 4.058	9.826 ± 4.746	− 4.058	< 0.001*

Data are mean ± SD for all variables
hs-CRP highly sensitive C-reactive protein, IL-6 interleukin-6, LDL low-density lipoprotein, HDL high-density lipoprotein, ALT alanine transaminase, AST aspartate transaminase, CK-T total creatine kinase
*Independent sample t test

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