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  1. Direct-acting antivirals (DAAs) have revolutionized the therapy of HCV infection with higher sustained virological response (SVR) rates. Fibrosis regression after achieving SVR to DAA remains to be evaluated i...

    Authors: Ramy H. Agwa, Mohamed H. Elgazzar, Islam A. El-Zayyadi, Ahmed M. Saed, Mayada A. Ghannam and Ahmed Saleh
    Citation: The Egyptian Journal of Internal Medicine 2022 34:18
  2. Primary IgA nephropathy (IgAN) has variable distribution and clinicopathological spectrum throughout the world. We report the incidence, demographic, and clinicopathological profile of primary IgAN from a tert...

    Authors: Mohammad Ashraf Bhat, Imran Sultan Sofi, Rayees Yousuf Sheikh and Imtiyaz Wani
    Citation: The Egyptian Journal of Internal Medicine 2022 34:17
  3. Laryngopharyngeal reflux (LPR) is caused by the regurgitation of gastric contents above the upper esophageal sphincter. Diagnostic gold standard tests like multichannel intraluminal impedance (MII) and 24-h du...

    Authors: Manal Sabry, Tarek Mohamed Yosef, Ahmed Mohammed Mahmoud and Tari M. A. George Michael
    Citation: The Egyptian Journal of Internal Medicine 2022 34:16
  4. Nesfatin-1 as a potent anorexigenic peptide is secreted by pancreatic β cells. Conflicting data are available about its level among diabetic patients. Our study aimed to assess nesfatin-1 levels in newly diagn...

    Authors: Ragaa Abdelshaheed Matta, Sahar Hossam El-Hini, Ahmed Mohamed Saad Eldin Salama and Hend Mohamed Moaness
    Citation: The Egyptian Journal of Internal Medicine 2022 34:15
  5. Tumor-induced osteomalacia (TIO) is a rare condition with fewer than 500 cases reported in the literature although described. Phosphaturic mesenchymal tumor (PMT) is often unrecognized cause of hypophosphatemi...

    Authors: Peikai Huang, Mengqiang Xiao, Meng Zhang, Jun Chen, Jingzhi Ye, Meiyi Zhao and Jiahui Tang
    Citation: The Egyptian Journal of Internal Medicine 2022 34:14
  6. Repeated attacks of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have been attributed to bacterial infections. However, sputum microbiology for identifying the bacteriological profile ...

    Authors: Narayan Mood, Surendar Reddy Katta, Aruna Kumari Badam and Jayaram Chundru
    Citation: The Egyptian Journal of Internal Medicine 2022 34:13
  7. In India, approximately 75% of population that is over 650 million people have B12 deficiency majority of which is caused by variation in demography, diet, and religion. Conditions such as smoking, alcohol, an...

    Authors: Sangita V. Patel, Alpesh B. Makwana, Archana U. Gandhi, Greenam Tarani, Jesal Patel and Vipul Bhavsar
    Citation: The Egyptian Journal of Internal Medicine 2022 34:11
  8. Acute hyperglycemia is a common finding in both diabetic and non-diabetic patients with acute coronary syndrome (ACS) who present to the emergency department (ED). The prognostic role of hyperglycemia in diabe...

    Authors: Yehia Mostafa Ghanem, Mona Wagdy Ayad, Azza Abdel Kareem, Maged Osama Guirguis, Asmaa Mohamed Alkafafy and Mai Hesham Badrah
    Citation: The Egyptian Journal of Internal Medicine 2022 34:10
  9. Solid pseudo-papillary neoplasm (SPPN) is a rare type of pancreatic tumor accounting for less than 2% of all pancreatic neoplasms. Accurate diagnosis of these tumors is very important for proper management. In...

    Authors: Hussein Okasha, Wael Abbas, Ahmed Altonbary, Hazem Hakim, Mahmoud Gamal Ameen and Mohamed El-Nady
    Citation: The Egyptian Journal of Internal Medicine 2022 34:9
  10. Hepcidin is the central regulatory molecule of systemic iron homeostasis. Serum ferritin, insulin resistance (IR) and metabolic syndrome (MetS), female sex hormones, and abdominal fat distribution are related ...

    Authors: Ragaa Abdelshaheed Matta, Mohamed Emad AbdElftah, Mohamed Gaber Essawy and Ahmed Abdelfadel Saedii
    Citation: The Egyptian Journal of Internal Medicine 2022 34:8
  11. Choledochal cysts (CDCs) are characterized by congenital cystic dilations of the intrahepatic or extrahepatic bile ducts or both. CDCs are very rarely reported in sub-Saharan Africa. This congenital anomaly of...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Andry Lalaina Rinà Rakotozafindrabe, Sakaiza Malala Randrianambininjanahary, Nitah Harivony Randriamifidy, Domoina Harivonjy Hasina Laingonirina, Sonny Maherison, Lova Hasina Ny Ony Narindra Rajaonarison, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa and Rado Manitrala Ramanampamonjy
    Citation: The Egyptian Journal of Internal Medicine 2022 34:7
  12. HCV infection is associated with increased risk of ischemic cerebral stroke. HCV stroked patients are younger with a lower burden of classical risk factors and higher levels of systemic inflammation. The prese...

    Authors: Mohammed M. Masoud, Hany A. Sayed, Hatem A. El Masry and Shaimaa A. Abdelkareem
    Citation: The Egyptian Journal of Internal Medicine 2022 34:6
  13. The deadly SARS-CoV-2 virus has infected more than 259,502,031 confirmed cases with 5,183,003 deaths in 223 countries during the last 22 months (Dec 2019–Nov 2021), whereas approximately 7,702,859,718, vaccine...

    Authors: Waqar Ahmad and Khadija Shabbiri
    Citation: The Egyptian Journal of Internal Medicine 2022 34:5
  14. The major cause of morbidity and mortality in diabetes is cardiovascular disease, which is exacerbated by the presence of hypertension. Therefore, proper control of BP in diabetic hypertensive patients is esse...

    Authors: Lobna F. El Toony, Andrew N. Ramzy and Mohamed A. A. Abozaid
    Citation: The Egyptian Journal of Internal Medicine 2022 34:4
  15. Obesity is an independent risk factor for chronic kidney disease (CKD) and is the strongest known modifiable risk factor for hyperuricemia and gout. We aimed to discover the outcome of serum uric acid (SUA), g...

    Authors: Mona G. Balata, Ahmed H. Helal, Ashraf H. Mohamed, Alaa-Uddin Habib, Mahmoud Awad and Mohamed Sherif
    Citation: The Egyptian Journal of Internal Medicine 2022 34:3
  16. For many years, esophageal manometry has been used for assessment of upper gastro-intestinal (GI) symptoms. Chicago classification is the key for diagnosis and managing motility disorders as it is considered a...

    Authors: Gina Gamal Naguib, Mohamed Hassan, Ahmed I. Elshafie and M. G. Naguib
    Citation: The Egyptian Journal of Internal Medicine 2022 34:2
  17. Indoxyl sulfate (IS) is produced by action of the intestinal flora on tryptophan in protein diet, and it is normally excreted by the kidney. IS is a protein-bound uremic toxin, and it is difficult to be remove...

    Authors: Mohamed Saeed Hassan, Yasser Soliman Ahmed, Eman Ibrahim Sarhaan, Nayra Shaker Mehanna, Norhan Nagdy Madbouli and Mostafa Abdelnasier Abdelgawad
    Citation: The Egyptian Journal of Internal Medicine 2022 34:1
  18. Patients with renal failure suffer from fluid overload which is a risk factor for mortality and morbidity. Therefore, fluid status assessment in patients on regular hemodialysis is very important. Dry weight a...

    Authors: Mohamed Abd El Hamid Hafiz, Emad Allam Mohamed, Mohamed Abo El Naga Mohamed and Mohamed Ahmed El Sayed Ahmed
    Citation: The Egyptian Journal of Internal Medicine 2021 33:43
  19. JAK (Janus kinase) inhibitors work by inhibiting the activity of one or more of the enzyme Janus kinase with a therapeutic application for treatment of cancer and inflammatory disorders such as rheumatoid arth...

    Authors: Yasmin Adel, Mohamed Sabry, Amr Mohamed El-Sabbagh and Yousra Sadeq
    Citation: The Egyptian Journal of Internal Medicine 2021 33:56
  20. Brucellosis is an anthropozoonosis. It is an endemic disease in the Mediterranean basin. The clinical presentation is polymorphic. The osteoarticular form is the most frequent of the focal forms affecting main...

    Authors: Lamia Oulkadi, Bouchra Amine, Imane El binoune, Samira Rostom and Rachid Bahiri
    Citation: The Egyptian Journal of Internal Medicine 2021 33:55
  21. Liver stiffness measurement (LSM) using transient elastography (TE) is a common noninvasive method for assessing hepatic fibrosis. The purpose of this study was to show the utility of LSM in the evaluation and...

    Authors: Hend Elsaied Ebada, Mohamed Fawzy Montasser, Eman Fathy Barakat, Sara Mahmoud Abdelhakam, Mohamed Shaker Ghazy and Ahmed Talaat Elganzory
    Citation: The Egyptian Journal of Internal Medicine 2021 33:41
  22. Multiple myeloma is a hematological malignancy of plasma cells belonging to a spectrum of monoclonal protein-secreting disorders known as paraproteinemias. It is classically characterized by accumulated plasma...

    Authors: Erick Thokerunga, Christopher Ntege and Abdullahi Omar Ahmed
    Citation: The Egyptian Journal of Internal Medicine 2021 33:54
  23. HCV infection is a major health concern. Disease progression to fibrosis, cirrhosis, and HCC is aided by the persistence of inflammatory reactions and cellular damage. Moreover, angiogenesis was found to have ...

    Authors: Amira Isaac, Tarek Maged El Sakaty, Sarah Hamdan Hussein and Hany Samir Rasmy
    Citation: The Egyptian Journal of Internal Medicine 2021 33:53
  24. Pyoderma gangrenosum (PG) is a rare and chronic neutrophilic dermatosis. It is clinically characterized by aseptic ulcerations preferentially located in the lower limbs. Its location in the genital area is unu...

    Authors: Hassina Chicha, Said Taharboucht, Nacera Tiboune, Nadia Touati and Ahcene Chibane
    Citation: The Egyptian Journal of Internal Medicine 2021 33:52
  25. Adolescents with coronavirus disease 2019 (COVID-19) associated multisystem inflammatory syndrome (MIS) can present with shock and myocardial injury and mimic Kawasaki disease.

    Authors: Rahul D. Bhiwgade, M. C. Nischitha, Bhushan Shahare and Shobhna Bitey
    Citation: The Egyptian Journal of Internal Medicine 2021 33:51
  26. Mycobacterium massiliense is a rapidly growing a non-tuberculous mycobacterium that has been validated as a separate species from the Mycobacterium abscessus group. Only few antibiotics have demonstrated germicid...

    Authors: Haroon Nawaz, Ayesha A. Choudhry and William Morse
    Citation: The Egyptian Journal of Internal Medicine 2021 33:39
  27. Endometriosis is a condition in which tissue similar to the lining inside the uterus (called “the endometrium”) is found outside the uterus, where it induces a chronic inflammatory reaction that may result in ...

    Authors: Nadia Abdelaaty Abdelkader, Ahmed F. Sherief, Enass Mohamed Soliman, Mahmoud Elsamman, Salah T. Fayed and Mohamed A. Sakr
    Citation: The Egyptian Journal of Internal Medicine 2021 33:50
  28. Psoriasis is a multisystem inflammatory disorder with variable morphology, clinical pattern and multiple comorbidities. Interplay between genetic and environmental factors leading to an aberrant immune respons...

    Authors: Enas Zahran, Ali Youssof, Wafaa Shehata, Ahmed Bahgat and Emad Elshebiny
    Citation: The Egyptian Journal of Internal Medicine 2021 33:49
  29. Early management of sepsis in the emergency department improves patient outcomes. The identification of at-risk patients for aggressive management by an easily available biomarker could go a long way in the tr...

    Authors: Mir Nadeem, Bilal Ahmad Mir, Mir Waseem, Tabinda Ayub Shah and Rameez Raja
    Citation: The Egyptian Journal of Internal Medicine 2021 33:48
  30. Co-occurrence of Type II Abernethy malformation (AM) with Type 1 pulmonary hypertension (PH) is extremely rare. In these patients, management of AM leads to reversal of PH.

    Authors: Arjun Agarwal, Durvesh Bhangale, Vinayak M. Sawardekar and Srikar Puvvada
    Citation: The Egyptian Journal of Internal Medicine 2021 33:38
  31. In this pandemic of COVID-19, the highest amount of infective material, biomedical waste is generated in hospitals and it is frequently handled by the healthcare workers irrespective of cadres. Hence the aware...

    Authors: T. J. Basavaraj, B. L. Shashibhushan and Amala Sreedevi
    Citation: The Egyptian Journal of Internal Medicine 2021 33:37
  32. Alzheimer’s disease (AD), cardiovascular disease (CVD), and diabetes are some of the most common causes of morbidity and mortality among the aging populations and cause a heavy burden on the worldwide healthca...

    Authors: Agnila Chakraborty, Saad Ahmed Sami and Kay Kay Shain Marma
    Citation: The Egyptian Journal of Internal Medicine 2021 33:47
  33. Hepatocellular carcinoma is a highly prevalent tumor worldwide. Amphiregulin is a ligand of the epidermal growth factor receptor. Its elevation is linked to different inflammatory and neoplastic conditions. Th...

    Authors: Amira Isaac, Sherif Mounir Mohamed, Osama Ashraf Ahmed, Ahmed Gamal Mohamed Hassan and Hany Samir Rasmy
    Citation: The Egyptian Journal of Internal Medicine 2021 33:46
  34. The association between hepatitis C virus (HCV), insulin resistance (IR), and metabolic syndrome has been extensively investigated. Direct-acting antivirals (DAAs) have a high sustained virologic response (SVR...

    Authors: Tarek Yosef, Wesam Ahmed Ibrahim, Ahmed El-Ghandour, Soha Attia and Sarah El-Nakeep
    Citation: The Egyptian Journal of Internal Medicine 2021 33:45
  35. Hypercalcemia is known to cause acute kidney injury (AKI). Literature related to hypercalcemic AKI is predominantly in the form of case reports and case series. The purpose of this study is to find the inciden...

    Authors: Nucksheeba Aziz Bhat, Farhat Mustafa, Rayees Yousuf Sheikh and Imtiyaz Wani
    Citation: The Egyptian Journal of Internal Medicine 2021 33:36
  36. Hodgkin’s lymphoma presenting with digital ischemia and gangrene is a rare manifestation. Paraneoplastic manifestations are rare in Hodgkin’s lymphoma but can occur in the form of paraneoplastic cerebellar deg...

    Authors: Swaroopa Deme, Bhaskar Kakarla, Venkateswar Rao P., Raju YSN and Nageswara Rao M.
    Citation: The Egyptian Journal of Internal Medicine 2021 33:44
  37. Indirect calorimetry is the reference method for measuring resting energy expenditure (REE), but the necessary equipment and technical expertise are not always available. Meanwhile, the NUTrition Risk in the C...

    Authors: Elham Sobhy, Radwa Abdel Kader, Alshaimaa Aboulfotouh, Mohammed Eshra and Mohamed Sayed
    Citation: The Egyptian Journal of Internal Medicine 2021 33:35
  38. Diabetes is a rapidly growing health problem worldwide. In 2019, the International Diabetes Federation (IDF) estimates that Egypt is the 9th country worldwide with about 8,850,400 cases and a prevalence of 15....

    Authors: Mai Mohamed Azzam, Adel Alwehedy Ibrahim and Mohammed I. Abd El-Ghany
    Citation: The Egyptian Journal of Internal Medicine 2021 33:33
  39. Coronavirus disease 2019 (COVID-19) is a recent pandemic infectious disease caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). COVID-19 may lead to acute kidney injury (AKI).

    Authors: Hayder M. Al-kuraishy and Ali I. Al-Gareeb
    Citation: The Egyptian Journal of Internal Medicine 2021 33:34
  40. Hepatitis C virus and nonalcoholic steatohepatitis (NASH) are the most common causes of liver cirrhosis in Egypt. Increasing aging population is a worldwide issue, and societies are facing various problems, in...

    Authors: Ahmed Abdelghani, Maha Hosam El-Din Ibrahim, Osama Mohamady Mohamed, Sobhi Eid Rizk and Rabab Mahmoud Ahmed
    Citation: The Egyptian Journal of Internal Medicine 2021 33:32
  41. Acute-on-chronic liver failure (ACLF) has been recently defined as a clinical form including acute hepatic decompensation and high 28-day mortality. ACLF usually follows a precipitating event on the background...

    Authors: Marwa Lotfi El Sayed, Tarek El Sayed Gouda, E. L. Sayed Abdel Maksood Khalil, Mohammed Mohammed El Sayed Al Arman and Islam Eid Mohamed
    Citation: The Egyptian Journal of Internal Medicine 2021 33:31
  42. Diabetes mellitus (DM) is a chronic disease with debilitating complications. Patients with diabetes are recommended to take various self-management decisions and carry out complex care activities. Diabetes sel...

    Authors: Reham Abo Emara, Madeha Hamed, Mohamed Awad and Wael Zeid
    Citation: The Egyptian Journal of Internal Medicine 2021 33:30
  43. Angiogenesis is the development of new blood vessels from the existing vasculature, which is important in normal developmental processes. Angiogenesis is a key step in tumor growth, invasion, and metastasis. A...

    Authors: Gowtham Kumar Subbaraj, Yasam Santhosh Kumar and Langeswaran Kulanthaivel
    Citation: The Egyptian Journal of Internal Medicine 2021 33:29
  44. Prediabetes is considered a major risk factor for diabetes mellitus (DM), leading to microvascular and cardiovascular disorders. Myocardial performance index (MPI) is a non-invasive Doppler method for the dete...

    Authors: Hossam Eldin M. Mahmoud, Mohamed Alsenbesy, Gehad Osama Fawzy Sayed, Abdulla Eliaw Mohamed Ali and Ahlam M. Sabra
    Citation: The Egyptian Journal of Internal Medicine 2021 33:28
  45. The prevalence of diabetes mellitus is on rising trend in developing countries like India. In type 2 diabetes patients, albuminuria has been shown to predict development of dysfunction in other organ systems s...

    Authors: Jiteshri Mehta, Varsha Y. Godbole, Kedar G. Mehta and A. Lalithambigai
    Citation: The Egyptian Journal of Internal Medicine 2021 33:27
  46. Heart failure (HF) is a major health problem. Cardiac and renal diseases interact in a complex bidirectional manner in both acute and chronic settings. Renal dysfunction in the setting of heart failure, termed...

    Authors: Ahmed Aly Obiedallah, Ashraf Anwar E. L. Shazly, Noura Gamal Nasr and Essam M. Abdel Aziz
    Citation: The Egyptian Journal of Internal Medicine 2021 33:25