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  1. The pathogenesis of type 2 diabetes mellitus (T2DM) originates from multiple tissue defects. Environmental pollutants such like endocrine-disrupting chemicals (EDCs) have lately gotten special attention in tri...

    Authors: Yasmin Ibrahim Zanet, Enayat Mohamed Hashem, Mohammed Naguib Dessouky, Magdy Helmy Megalla and Iman Samy Dessouky
    Citation: The Egyptian Journal of Internal Medicine 2023 35:23
  2. Diabetic nephropathy (DN) is one of the major causes of ESKD, and its complications are characterized by proteinuria, decreased glomerular filtration, and renal fibrosis resulting in the deterioration of renal...

    Authors: Amr M. Shaker, Maggie E. Mohamed, Tarek Ramzy and Mayssa I. Ali
    Citation: The Egyptian Journal of Internal Medicine 2023 35:22
  3. With increasing healthcare demands for acute illness in patients especially in the times of pandemic, healthcare organizations require modern solutions. Hospital at home (HaH) is one such tool that has the pot...

    Authors: Sai Gautham Kanagala, Vasu Gupta, Sunita Kumawat, FNU Anamika, Brian McGillen and Rohit Jain
    Citation: The Egyptian Journal of Internal Medicine 2023 35:21
  4. Mycoplasma pneumoniae is one of the leading causes of community-acquired pneumonia. Due to its microbiological variation, clinical presentations of mycoplasma infections are atypical and diverse. Multiple pulmona...

    Authors: Namitha Mohan, Vishal Dnyaneshwar Sawant and Alpana Kondekar
    Citation: The Egyptian Journal of Internal Medicine 2023 35:20
  5. We present a case report of an immunocompromised adult with cytomegalovirus infection and APLA positivity complicated by multiple large arterial thrombi. This is a rare presentation as most of the cases report...

    Authors: Garyll Ryan Tariang Blah, Megha Pradeep, C. Shah Harshil and Rajnish Singh
    Citation: The Egyptian Journal of Internal Medicine 2023 35:19
  6. Hepatocellular carcinoma represents 85%—90% of primary liver tumors; it represents the 2nd leading cause of cancer-related death all over the world. There is a growing incidence of HCC worldwide and similarly, th...

    Authors: Ahmed Abdel Kareem Ali, Salah El Gamal, Rokiah Anwar, Eman Elzahaf and Dina Eskandere
    Citation: The Egyptian Journal of Internal Medicine 2023 35:18
  7. Systemic lupus erythematosus is a chronic multisystem disease that has a considerable morbidity and mortality. Rituximab is used in treating some severe manifestations of systemic lupus erythematosus; however,...

    Authors: Moustafa Ali Saad, Rania Farid Yacoub and Hala Ibrahem El Gendy
    Citation: The Egyptian Journal of Internal Medicine 2023 35:15
  8. The COVID-19 pandemic has been associated with millions of deaths around the world. One of the important causes of death associated with COVID-19 was pulmonary thromboembolism. The risk for venous thromboembol...

    Authors: Ahmed Elshafie, Enas Foda, Mahmoud M. G. Yousef and Kareem A. Abd El-Naby
    Citation: The Egyptian Journal of Internal Medicine 2023 35:14
  9. Hepatitis C is associated with metabolic effects and fatty liver disease. The effect of different direct antivirals on the liver steatosis, and the metabolic profile, still needs to be established. The aim of ...

    Authors: Ahmed El-Ghandour, Tarek Youssif, Wesam Ibrahim, Hoda Ahmed Abdelsattar, Somia Abd elhamid Bawady, Mariam Wagih and Sarah El-Nakeep
    Citation: The Egyptian Journal of Internal Medicine 2023 35:12
  10. Coronavirus disease 2019 (COVID-19) was previously thought to have a low reinfection rate, but there are concerns that the reinfection rate will increase with the emergence and spread of mutant variants. This ...

    Authors: Nagashige Shimada, Masahiro Shinoda, Hiroaki Takei, Yuto Yoshida, Masashi Nishimura, Mio Kousaka, Miwa Morikawa, Takashi Sato, Hiroto Matsuse and Masaharu Shinkai
    Citation: The Egyptian Journal of Internal Medicine 2023 35:13
  11. SARS-CoV-2, the causative agent of COVID-19, claimed multiple lives in a very short span of time. Seeing the urgency of situation, vaccines were developed in hitherto unseen time frame. Vaccines definitely pas...

    Authors: Shahnawaz Muslim, Gulam Mustafa, Nasrin Nasrin, Aaisha Firdaus and Shambhu Kumar Singh
    Citation: The Egyptian Journal of Internal Medicine 2023 35:11
  12. Large numbers of elderly patients are admitted to hospitals in acute confusional states. In many, the underlying causes are easily found; in some, correct diagnosis is difficult. Pulmonary embolism (PE), the m...

    Authors: Chidimma A. Ahaneku, Benard B. Akpu, Chibueze H. Njoku, David E. Elem and Bassey E. Ekeng
    Citation: The Egyptian Journal of Internal Medicine 2023 35:8
  13. Human monkeypox (MPOX) which recently hit the headlines is a rare, emerging zoonotic disease, only next to smallpox yet never attended adequately to halt the epidemic outbreak threat. MPOX is caused by Orthopox v...

    Authors: Naga Vishnu Kandra, Anjaly Mary Varghese, Praveen Kumar Uppala, Upendrarao Uttaravelli, Butti Lavanya, S. K. M. Shabana, Venkata Saibaba Somarouthu and Murali Krishna Balijepalli
    Citation: The Egyptian Journal of Internal Medicine 2023 35:10
  14. Since its discovery, COVID-19 has often been the first diagnosis of dyspnea and asthenia, especially during the pandemic waves. However, it is not always COVID-19. We report a particular case of a late-diagnos...

    Authors: Zamelina Angela Razafindrasoa, Sonia Marcelle Razafimpihanina, Marie Odette Rasoafaranirina, Fidy Arnauld Martin, Finaritra Princy Parfait Andriamahenina, Diamondra Ombanjanahary Andriarimanga, Jocelyn Robert Rakotomizao, Harison Michel Tiaray, Joëlson Lovaniaina Rakotoson and Rondro Nirina Raharimanana
    Citation: The Egyptian Journal of Internal Medicine 2023 35:9
  15. The spectrum of gastrointestinal (GI) issues in the older population varies from common physiological age-related changes to devastating, less common sinister pathological illness. GI system has direct exposur...

    Authors: Saurabh Dawra, Pradeep Behl, Sharad Srivastava, Manish Manrai, Alok Chandra, Anupam Kumar, Ankit Kumar and Manveer Singh Tevatia
    Citation: The Egyptian Journal of Internal Medicine 2023 35:7
  16. Unusual fungal agents that exist environmentally as saprophytes can often lead to opportunistic infections, hyalohyphomycosis is a group of fungal infections caused by fungi characterized by hyaline septate hy...

    Authors: Hamdy Ibrahim, Mostafa ALfishawy, Attaa Ali, Safwat Abdel Maksod, Magdy Khorshed, Hanan Rady, Ahmed Alsisi, Adel Mohamed, Omar Alkassas, Marwa Haron and Suzan Saied
    Citation: The Egyptian Journal of Internal Medicine 2023 35:5
  17. Vascular calcification is a significant risk factor for cardiovascular diseases in patients with end-stage renal disease, particularly those on hemodialysis. Previous research on vitamin K found that it had a ...

    Authors: Howaida Abdelhameed Elshinnawy, Tamer Wahid El-Said, Sarah Farid Fahmy, Ahmed Shamseldin, Sherin Ibrahim and Reem Mohsen Elsharabasy
    Citation: The Egyptian Journal of Internal Medicine 2023 35:4
  18. Chronic kidney disease is a growing worldwide public health concern. On the other hand, patients’ perception of health is an important outcome measure in the assessment of the influence of chronic disease and ...

    Authors: Brunilda Elezi, Merita Rumano, Erjona Abazaj and Skender Topi
    Citation: The Egyptian Journal of Internal Medicine 2023 35:3
  19. There are two forms of hyper-immunoglobulin E syndromes (HIES): a dominant form (AD-HIES) is caused by mutations in signal transducer and activator of transcription 3 (STAT3), and a recessive form (AR-HIES) is...

    Authors: Hamdi Ibrahim, Safwat Abdel Maksod, Magdy Khorshed, Hanan Rady, Marwa Haron, Omar Alkassas, Ahmed Alsisi, Suzan Said, Mostafa ALfishawy and Adel Mohamed
    Citation: The Egyptian Journal of Internal Medicine 2023 35:2
  20. Western Kenya, being a malaria-endemic region, has a high prevalence of hemoglobinopathies mostly sickle cell and thalassemia. The hemoglobin fractions or variants, HbA, HbA2, and HbF, serve as biomarkers for ...

    Authors: Benard Mutua, Rose Chelangat, Barasa Mustafa, Tom Were, Julie Makani, George Sowayi and Patrick Okoth
    Citation: The Egyptian Journal of Internal Medicine 2022 34:95
  21. Diabetes mellitus is a complex chronic disease characterized by chronic hyperglycemia resulting from defective insulin secretion, defective insulin action, or both. Chronic hyperglycemia related to diabetes ca...

    Authors: Marwa Sayed Eissa, Sahar Abou-ElEzz, Samar Mohsen Kanzel and Mohamed Mady
    Citation: The Egyptian Journal of Internal Medicine 2022 34:94
  22. Pulmonary cyst is a rounded lung parenchymal lucency, usually containing air or fluid. Approach to establishing the etiology of lung cyst includes determining their location, number, distribution, and presence...

    Authors: Amit Panjwani and Mohamed Redha Salman
    Citation: The Egyptian Journal of Internal Medicine 2022 34:93
  23. It has been documented that nearly 600 million people worldwide are expected to have diabetes mellitus in 2035 and that approximately 140,000 persons aged 20–69 years living with diabetes mellitus in Trinidad ...

    Authors: Rachel Leah Vincent-Edinboro and Philip Onuoha
    Citation: The Egyptian Journal of Internal Medicine 2022 34:92
  24. According to the World Health Organization (WHO), quality of life is “an individual’s perception of their position in life in the context of the culture and value systems in which they live, and in relation to...

    Authors: Maha Hossam AL-Din, Bodour Magdy and Hala Ramadan
    Citation: The Egyptian Journal of Internal Medicine 2022 34:91
  25. The famed variola (smallpox) virus and the monkeypox virus (MPXV) are closely related, and MPXV causes a milder form of febrile rash disease in people. Human monkeypox was mostly an uncommon zoonotic illness t...

    Authors: Samiksha Jayswal and Jagdish Kakadiya
    Citation: The Egyptian Journal of Internal Medicine 2022 34:90
  26. Anomalous left coronary arteries are rare congenital defects. These are often detected incidentally unless they have a malignant course whereby patients present with acute coronary syndromes. We describe a rar...

    Authors: Umar Syed Ali, Agneta Geldenhuys, Jacobus Otto, Rafeeq Samie, Girish Dwivedi, David Andrews and Abdul Rahman Ihdayhid
    Citation: The Egyptian Journal of Internal Medicine 2022 34:89
  27. Polycythemia refers to a condition of an abnormal increase in the red blood cell (RBC) mass. In men with a hematocrit > 60% or women with a hematocrit > 55%, there is 99% likelihood that the RBC mass is elevat...

    Authors: Premapassan Krishnamurthy, Garyll Ryan Tariang Blah, Madhu Bala Negi, Gunjan Lalwani and C. Shah Harshil
    Citation: The Egyptian Journal of Internal Medicine 2022 34:88
  28. Multiple case reports and case series have been published on heart failure due to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs), yet the management and outcome of the said disease hav...

    Authors: Mohammad Nawaf AlShatnawi, Rzan Atef Shawashreh, Mohammed Ashraf Sunoqrot and Ali Rezeq Yaghi
    Citation: The Egyptian Journal of Internal Medicine 2022 34:85
  29. Copper sulfate is a bright blue crystal used primarily for agricultural purposes, as a pesticide, disinfectant, feed, and soil additive. Acute volunteer poisoning of copper sulfate is not common in the world a...

    Authors: Samaneh Hajimohammadi, Somayeh Gharibi, Vahid Pourbarkhordar, Seyed Reza Mousavi and Hanieh Salmani Izadi
    Citation: The Egyptian Journal of Internal Medicine 2022 34:84
  30. Malnutrition is a common problem among patients with inflammatory bowel disease and up to 18–62% of ulcerative colitis (UC) patients were reported to be malnourished. This study aimed to assess micronutrient s...

    Authors: Amany Hussien, Sawsan Abd El-Moniem, Ziyad Tawhid and Ahmed Altonbary
    Citation: The Egyptian Journal of Internal Medicine 2022 34:83
  31. Susac syndrome is a rare disease with multisystem manifestations. While the exact pathogenesis is not known, it has been proposed to be an autoimmune endotheliopathy affecting the microvasculature of the brain...

    Authors: Sabeeh Ahmed, Taimoor A. Khan, Talha Liaqat, Umer Ijaz and Haroon Sarfaraz
    Citation: The Egyptian Journal of Internal Medicine 2022 34:82
  32. Myelofibrosis (MF) is a haematopoietic stem cell tumour caused by the lack of BCR-ABL translocation due to point mutations in Janus kinases (JAKs). In previous years, dealing with MF included several protocols...

    Authors: Amr Ghit
    Citation: The Egyptian Journal of Internal Medicine 2022 34:81
  33. Research has shown that health care personnel is at higher risk of acquiring the disease than the general population. In spite of this challenge, there has been a low vaccination record among the Health Workers

    Authors: Oluwatosin Idowu Oni, Olanrewaju Patrick Osho, Mathew Temitope Oluwole, Evelyn Salewa Osho, Aanuoluwapo Ogungbeje and Habeebat Motunrayo Raji
    Citation: The Egyptian Journal of Internal Medicine 2022 34:80
  34. Psoriasis is a chronic inflammatory disorder of the skin; the hallmark of psoriasis is sustained inflammation that leads to uncontrolled keratinocyte proliferation and dysfunctional differentiation. Psoriasis ...

    Authors: Marouane Jabrane, Abderrahim Wakrim and Mohammed Arrayhani
    Citation: The Egyptian Journal of Internal Medicine 2022 34:79
  35. Diabetes and stroke prevalence rates are increasing worldwide, and both are major human health threats causing disability and death. Diabetes is a well-known independent risk factor for stroke. In addition, di...

    Authors: Eman Yousef Morsy, Kamel Hemida Rohoma, Shimaa Ali Mohamed Ali and Salah Hussein Elhalawany
    Citation: The Egyptian Journal of Internal Medicine 2022 34:78
  36. Simultaneous increase in transaminases and bilirubin is an indicator of hepatic dysfunction in malaria. Malaria-induced hyperbilirubinemia has been associated with acute kidney injury and pathogenesis of cereb...

    Authors: Rotimi Johnson Ojo, Isaac Gladson Jonathan, Moses Dele Adams, Gideon Gyebi and Ishaya Yohanna Longdet
    Citation: The Egyptian Journal of Internal Medicine 2022 34:77
  37. The COVID-19 pneumonia is a heterogeneous disease with variable effect on lung parenchyma, airways, and vasculature leading to long-term effects on lung functions.

    Authors: Shital Patil, Gajanan Gondhali and Abhijit Acharya
    Citation: The Egyptian Journal of Internal Medicine 2022 34:75
  38. Hemophilia is an inherited condition that is caused by the deficiency of clotting factors in the blood. The most common presentations of hemophilia are hemarthrosis and muscle hemorrhage. The severity of the b...

    Authors: Osama Ahmed Ibrahiem, Ahmad F. Thabet, Shymaa S. Tony, Kerollos Motwade N. Kerollos and Sawsan M. Moeen
    Citation: The Egyptian Journal of Internal Medicine 2022 34:74
  39. Triad of diabetic ketoacidosis (DKA) comprises of hyperglycemia with serum glucose > 11 mmol/L, high anion gap metabolic acidosis and ketonemia. Hyperlactemia is often noted in patients with DKA. Metformin use...

    Authors: Yudara Kularathne, Shaun Goh and Sohil Pothiawala
    Citation: The Egyptian Journal of Internal Medicine 2022 34:73
  40. Zinc is an anti-inflammatory and antioxidant micronutrient found in food. Due to its well-established role in immunity, it is currently being used in some clinical trials against coronavirus disease-2019 (COVI...

    Authors: Ahmed M. F. Mansour, Noha El Nakeeb, Norhan Khaled Mohamed Kamal and Ahmed Mohamed ElGhandour
    Citation: The Egyptian Journal of Internal Medicine 2022 34:72
  41. Literatures revealed syndrome of inappropriate antidiuretic hormone (SIADH) as the most common mechanism of hyponatremia in COVID-19. However, it is important to rule out other etiologies of hyponatremia.

    Authors: Ahmad Nasrat Al-juboori, Amira Al Hail and Zaid Ahmad Al-juboori
    Citation: The Egyptian Journal of Internal Medicine 2022 34:71
  42. Malnutrition is highly prevalent in chronic kidney disease (CKD). This study is conducted to find out the prevalence of malnutrition and its association with inflammation in patients with CKD stages 3–5.

    Authors: Rayees Yousuf Sheikh, Hamad Jeelani Samoon, Nucksheeba Aziz Bhat and Imtiyaz Wani
    Citation: The Egyptian Journal of Internal Medicine 2022 34:70
  43. Dyslipidemia is a common finding in primary nephrotic syndrome (PNS). Serum PCSK9 level is also increased in PNS and is the main cause of dyslipidemia in such patients. There is a paucity of data on the relati...

    Authors: Howayda El Shinnawy, Abubakr Mohamed Fahmy and Mohamed Sary Gharib
    Citation: The Egyptian Journal of Internal Medicine 2022 34:69