Fig. 1

The course of symptoms and treatments from infection with the E484K variant to infection with the N501Y variant. The severity was mild in both the initial infection (E484K variant) and the reinfection (N 501Y variant). In the initial infection, he was relieved in about 3 to 4 days with only symptomatic treatment, but in the reinfection, his fever was bimodal, and he had persistent symptoms. Abbreviations: methylprednisolone, mPSL; azithromycin, AZM; ceftriaxone, CTRX