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Table 4 Comparison between group 1 (pts received viral vector-based vaccines with adverse events) vs group 3 (pts received inactivated virus-based vaccines with adverse events)

From: Immune-mediated adverse events post-COVID vaccination and types of vaccines: a systematic review and meta-analysis

 

Group 1 (viral vector vaccine)

Percentage

Group 3 (inactivated virus vaccine)

Percentage

DIFF/95 CI/chi-squared/DF/significance

Thrombosis/thrombocytopenia

236

51.30%

0

0%

51.3%/46.6659–55.8379%/317.046/1/p < 0.0001

ICH

33

7%

0

0%

7%/4.8418–9.7052%/33.332/1/p < 0.0001

DIC

5

1%

0

0%

1%/− 0.0148–2.3981%/4.618/1/p = 0.0316

GBS

16

4%

0

0%

4%/2.3366–6.2045%/18.755/1//p < 0.0001

Acute TM

7

2%

1

0.20%

1.8%/0.4357–3.5402%/6.842/1/p = 0.0089

Acute demyelinating polyradiculopathy

2

0.40%

0

0%

.4%/− 0.4793–1.5170%/1.842/1/p = 0.1748

Acute disseminated encephalomyelitis

1

0.20%

0

0%

.2%/−0.6448–1.1916%/0.920/1/p = 0.3375

Inflammatory myositis

3

0.60%

0

0%

.6%/− 0.3215–1.8223%/2.765/1/p = 0.0963

Erythema nodosum

1

0.20%

0

0%

0.2%/− 0.6448–1.1916%/0.920/1/p = 0.3375

Renal complication

3

0.60%

1

0.20%

.4%/− 0.6708–1.6336%/0.923/1/p = 0.3368

Acute macular neuroretinopathy/facial palsy/choroiditis

7

2%

1

0.20%

1.8%/0.4357–3.5402%/6.842/1/p = 0.0089

Cutaneous vasculitis

0

0.00%

0

0%

0%/− 0.8282–0.8282%

Myocarditis

0

0.00%

0

0%

0%/− 0.8282–0.8282%

Acute myocardial infarction

0

0.00%

0

0%

0%/− 0.8282–0.8282%

ITP

0

0.00%

0

0%

0%/− 0.8282–0.8282%

Miller Fisher S

0

0.00%

0

0%

0%/− 0.8282–0.8282%

Sarcoid reaction

0

0.00%

0

0%

0%/− 0.8282–0.8282%

Steven Johnson Syndrome

0

0.00%

0

0%

0%/− 0.8282–0.8282%

Uveitis

0

0.00%

1

0.20%

.2%/− 0.6448–1.1916%/0.920/1/P = 0.3375

  1. ICH intracranial hemorrhage, DIC disseminated intravascular coagulopathy, GBS Guillian Barre Syndrome, ATM acute transverse myelitis, ADPR acute demyelinating polyradiculopathy, ADEM acute disseminated encephalomyelitis, ITP idiopathic thrombocytopenic purpura