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Table 1 Demographic data, inflammatory markers, mean serum TNF alpha, IL6, and gene mutation of RA patients and control subjects

From: JAK2 mutation may predict response and guide first line treatment in rheumatoid arthritis

  

Patients

Control

Sexa

Male

14 (16.5%)

13 (26%)

Female

71(83.5%)

37 (74%)

Age years

Range

36–65

33–61

Mean ± SD

48.7 ± 7.2

42 ± 6.1

ESR mm/h

Mean ± SD

47.9 ± 17.7a

11 ± 4

CRP mg/L

Mean ± SD

33.2 ± 27.8a

6 ± 5.2

TNF-alpha pg/ml

Mean ± SD

38.4 ± 36.5a

19.2 ± 5.4

IL-6 pg/ml

Mean ± SD

66.3 ± 55.6a

13.1 ± 2.7

JAK2

Mutant

45 (52.9%)

0 (0%)

Non-mutant

40 (47.1%)

50 (100%)

  1. aAll patients are newly diagnosed at time of study inclusion