Utility of transient elastography in evaluation and follow-up of Budd-Chiari syndrome patients after endovascular intervention

The Egyptian Journal of Internal Medicine

Table 1 Characteristics of patients before and after endovascular intervention

Characterstics of patients^a (n = 24)	Pre-intervention	Post-intervention	p value
Clinical
Jaundice	4 (16%)	0	0.13
Encephalopathy	2 (8%)	0	0.5
LL edema	14 (56%)	0	< 0.001
Abdominal enlargement	14 (56%)	0	< 0.001
Tender liver	17 (68%)	5 (20.8%)	0.003
Laboratory
Bilirubin	1.16 ± 0.49	0.97 ± 0.21	0.02
ALT	33.12 ± 8.71	22.96 ± 7.18	< 0.001
AST	25.80 ± 8.3	17.46 ± 6.268	< 0.001
Radiological (Duplex ultrasound)
Ascites	Grade 1: 11	No ascites 18	< 0.001
	Grade 2: 9	Grade 1: 6
	Grade 3: 4
Hepatomegaly	18 (72%)	18 (72%)	1
Intrahepatic collaterals	7 (28%)	0	< 0.001
HVPG	23.80 ± 6.55 (15–40)	8.00 ± 2 (4–12)	< 0.001
LSM mean (range)	51.62 ± 22 (11.4–75)	28.80 ± 19.25 (8.7–75)	< 0.001
Liver biopsy (METAVIR staging)	F1:7 (28%) F2: 6 (24%) F3: 3(12%) F4: 9(36%)

^aClinical, laboratory, and radiological characteristics (Duplex US) of the patents were assessed once before and again 3 months post-intervention. HVPG was measured immediately before and after intervention. Liver biopsy was done only during the procedure using transvenous approach (i.e., before the endovascular intervention)