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Table 2 Studies assessing the effectiveness of AVR in patients with Heyde’s syndrome

From: Reappraising the spectrum of bleeding gastrointestinal angioectasia in a degenerative calcific aortic valve stenosis: Heyde’s syndrome

Study

Age (years)

Follow-up

Summary of findings

Mirna et al. [45] 2019, Austria

73

3 months

Normal quantity of vWF multimers, normal Hb concentration

Ramachandran et al. [46] 2018, USA

85

6 months

No need for blood transfusion with a normal Hb concentration

Alshuwaykh et al. [47] 2018, USA

56

6 months

No further episodes of GI bleeding

Iijima et al. [48] 2018, Japan

77

20 months

Cessation of recurrent GI bleeding

Shibamoto et al. [49] 2017, Japan

87

20 months

No episodes of GI bleeding and no need for blood transfusion

Balbo et al. [50] 2017, Brazil

81

6 months

No episodes of recurring GI bleeding

Benton et al. [51] 2014, USA

77

10 months

Normal levels of HMW vWF multimers and free from recurrent GI bleeding

Saad et al. [52] 2013, UK

76

4 months

Free from iron deficiency anemia

Pyxaras et al. [53] 2012, Italy

89

6 months

Normal hematological parameters with no episodes of GI bleeding

  1. vWF von Willebrand factor, Hb hemoglobin, HMW high molecular weight, GI gastrointestinal