Table 1 Studies evaluating the association between angioectasia and aortic stenosis
Source | Study design | Number of participants or events | Summary of findings |
|---|---|---|---|
Batur et al. [30] 2003, USA | Retrospective study | 92,075 | 2.3-fold increase in the prevalence of AS of any severity in patients with GI AVMs compared with the general population [31.7%, 14.0%; P<0.001] 4.1-fold increase in severe AS in the AVMs group compared with the general population [14.3% vs 3.5%; P<0.001] |
Pate et al. [31] 2004, Canada | Retrospective study | 3,800,000 | Significant association P<0.0001 between aortic stenosis and bleeding gastrointestinal angioectasia with an odds ratio of 4.5 (95% CI 3.0–6.8) |
Jehangir et al. [32] 2018, USA | Retrospective study | 32,079 | 7.02% prevalence of aortic valve disease in patients with bleeding intestinal angioectasia Adjusted odds ratio still reveals significant association (odds ratio = 2.37, 95% CI 2.10–2.66, P<0.001). |